Evidence map›Paper›PMID 29976412›Full record

ReviewJournal of food and drug analysis2018

Benefaction of probiotics for human health: A review.

Rout George Kerry, Jayanta Kumar Patra, Sushanto Gouda, Yooheon Park, Han-Seung Shin, Gitishree Das

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 324 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
324citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04322500 nacompletednot on this mapstarted 2019, after this paper: background citation

Intestinal Microbiota: a New Target for Chalaziosis Treatment in Children

TypeinterventionalSponsorUniversity of MoliseRan2019 to 2020Enrolled26ConditionsChalazionArmsprobiotics, conservative treatment
NCT04342507 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of Probiotic Oral Supplementation on the Treatment of Chalazion in Adults: a Pilot Study on 20 Patients

TypeinterventionalSponsorUniversity of MoliseRan2019 to 2020Enrolled20ConditionsChalazionArmsconservative treatment, probiotics
3 · Its place in the literature

Who cites it

324 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Frontiers in immunology · 2025
    Trial
  4. Review
  5. Article
  6. Review
  7. Anti-Inflammatory Potential ofMicroorganisms · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

264 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rout George KerryP.G. Department of Biotechnology, Academy of Management & Information Technology, Khurda, 752057, Odisha, India.
Jayanta Kumar PatraP.G. Department of Biotechnology, Academy of Management & Information Technology, Khurda, 752057, Odisha, India.
Sushanto GoudaAmity Institute of Wildlife Science, Noida, 201303, Uttar Pradesh, India.
Yooheon ParkResearch Institute of Biotechnology and Medical Converged Science, Dongguk University-Seoul, Gyeonggi-do, 10326, Republic of Korea.
Han-Seung ShinDepartment of Food Science and Biotechnology, Dongguk University-Seoul, Gyeonggi-do, 10326, Republic of Korea.
Gitishree DasResearch Institute of Biotechnology and Medical Converged Science, Dongguk University-Seoul, Gyeonggi-do, 10326, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans are a unique reservoir of heterogeneous and vivacious group of microbes, which together forms the human-microbiome superorganism. Human gut serves as a home to over 100-1000 microbial species, which primarily modulate the host internal environment and thereby, play a major role in host health. This spectacular symbiotic relationship has attracted extensive research in this field. More specifically, these organisms play key roles in defense function, eupepsia along with catabolism and anabolism, and impact brain-gut responses. The emergence of microbiota with resistance and tolerance to existing conventional drugs and antibiotics has decreased the drug efficacies. Furthermore, the modern biotechnology mediated nano-encapsulated multiplex supplements appear to be high cost and inconvenient. Henceforth, a simple, low-cost, receptive and intrinsic approach to achieve health benefits is vital in the present era. Supplementation with probiotics, prebiotics, and synbiotics has shown promising results against various enteric pathogens due to their unique ability to compete with pathogenic microbiota for adhesion sites, to alienate pathogens or to stimulate, modulate and regulate the host's immune response by initiating the activation of specific genes in and outside the host intestinal tract. Probiotics have also been shown to regulate fat storage and stimulate intestinal angiogenesis. Hence, this study aims to underline the possible beneficial impact of probiotics for human health and medical sectors and for better lifestyle.

Indexed as

AnimalsDiabetes MellitusGastrointestinal MicrobiomeHealthHumansNeoplasmsObesityProbioticsHuman-gutMicrobiotaPathogenicProbioticsSymbiotic relationship

Identifiers

PMID29976412
PMCPMC9303019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.