Evidence map›Paper›PMID 29976406›Full record

ArticleJournal of food and drug analysis2018

Simultaneous analysis of 23 illegal adulterated aphrodisiac chemical ingredients in health foods and Chinese traditional patent medicines by ultrahigh performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.

Xiao-Bing Wang, Jing Zheng, Jun-Jie Li, Hai-Ying Yu, Qi-Yan Li, Li-Hua Xu, Ming-Jie Liu, Rui-Qing Xian, Yang-En Sun, Bing-Jie Liu

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiao-Bing WangShandong Institute for Food and Drug Control, Jinan, China.
Jing ZhengShandong Institute for Food and Drug Control, Jinan, China.
Jun-Jie LiShandong Institute for Food and Drug Control, Jinan, China.
Hai-Ying YuShandong Institute for Food and Drug Control, Jinan, China.
Qi-Yan LiShandong Institute for Food and Drug Control, Jinan, China.
Li-Hua XuShandong Institute for Food and Drug Control, Jinan, China.
Ming-Jie LiuShandong Institute for Food and Drug Control, Jinan, China.
Rui-Qing XianShandong Institute for Food and Drug Control, Jinan, China.
Yang-En SunDong-E E-jiao Co., Ltd, National Engineering Technology Research Center of Gelatin Medicine, Shandong Province Key Laboratory of R&D of the Gelatin Medicine, Liaocheng, China.
Bing-Jie LiuShanghai AB Sciex Analytical Instrument Trading Co., Ltd, Shanghai, China.
Shandong Institute of Food and Drug Inspection · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper presents an application of ultra high-performance liquid-chromatography-quadrupole-TOF high resolution mass spectrometry (UHPLC-Q-TOF HRMS) for simultaneous analysis of 23 illegal adulterated aphrodisiac type chemical ingredients in health foods and Chinese Traditional Patent Medicines (CTPMs). The mass spectrometer was operated in Information Dependent Acquisition (IDA) mode, which provides crucial information for the elemental composition analysis, structure elucidation and quantitative analysis simultaneously. Quantitative analysis was performed using the peak areas of the precursor ions in the XICs. The method validation included assessment of selectivity, sensitivity, calibration curve, accuracy, precision, recovery, matrix effect and stability. The results show good linear relationship with the concentrations of the analytes over wide concentration ranges (e.g., 0.05-10 μg/g for sildenafil) as all the fitting coefficients of determination r

Indexed as

AphrodisiacsChromatography, High Pressure LiquidDrug ContaminationDrugs, Chinese HerbalFood ContaminationLimit of DetectionMass SpectrometryMedicine, Chinese TraditionalAphrodisiacsDrugs, Chinese HerbalAphrodisiac chemical ingredientsIllegal adulterationQ-TOF MSQualitationQuantitation

Identifiers

PMID29976406
PMCPMC9303026
OpenAlexW2792897215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.