ArticleJournal of food and drug analysis2018
Comprehensive quality evaluation and comparison of Angelica sinensis radix and Angelica acutiloba radix by integrated metabolomics and glycomics.
Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Life cycle, seasonal- and tissue-dependent metabolite composition, and high (E)-Ligustilide content characterize the ethnobotany of a Native American medicinal plant, Lomatium foeniculaceum.Journal of natural medicines · 2026Article
- Adulteration Identification of Angelica Sinensis Radix Based on Molecular Matrix Characteristics.Foods (Basel, Switzerland) · 2025Article
- Integrating DNA Barcoding Within an Orthogonal Approach for Herbal Product Authentication: A Narrative Review.Phytochemical analysis : PCA · 2025Review
- Identification of Angelica acutiloba, A. sinensis, and other Chinese medicinal Apiaceae plants by DNA barcoding.Journal of natural medicines · 2024Article
- The Dynamic Accumulation Rules of Chemical Components during the Medicine Formation Period ofMolecules (Basel, Switzerland) · 2023Article
- Studies on cultivation of Angelica acutiloba using paper pot (Part 2): effect of difference in taproot base diameter of seedlings on growth after planting and quality of toki produced from paper pot seedlings.Journal of natural medicines · 2021Article
- Screening study of blood-supplementing active components in water decoction ofPharmaceutical biology · 2020Article
- Quantification Analysis of 13 Organic Components and 8 Inorganic Elements inJournal of analytical methods in chemistry · 2020Article
- Comparative quality of the forms of decoction pieces evaluated by multidimensional chemical analysis and chemometrics: Poria cocos, a pilot study.Journal of food and drug analysis · 2019Article
- Simultaneous quantification combined with multivariate statistical analysis of multiple chemical markers of Wu Ji Bai Feng Pill by UHPLC-MS/MS.Journal of food and drug analysis · 2019Article
- Angelica Stem: A Potential Low-Cost Source of Bioactive Phthalides and Phytosterols.Molecules (Basel, Switzerland) · 2018Article
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Authors and funding
10 authors.
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Abstract
Angelica radix (Danggui in Chinese) used in China and Japan is derived from two species of Angelica, namely Angelica sinensis and Angelica acutiloba, respectively. The differences in quality between A. sinensis radix (ASR) and A. acutiloba radix (AAR) should be therefore investigated to guide the medicinal and dietary applications of these two species. Secondary metabolites and carbohydrates have been demonstrated to be the two major kinds of bioactive components of Danggui. However, previously, quality comparison between ASR and AAR intensively concerned secondary metabolites but largely overlooked carbohydrates, thus failing to include or take into consideration an important aspect of the holistic quality of Danggui. In this study, untargeted/targeted metabolomics and glycomics were integrated by multiple chromatography-based analytical techniques for qualitative and quantitative characterization of secondary metabolites and carbohydrates in Danggui so as to comprehensively evaluate and compare the quality of ASR and AAR. The results revealed that not only secondary metabolites but also carbohydrates in ASR and AAR were different in type and amount, which should collectively contribute to their quality difference. By providing more comprehensive chemical information, the research results highlighted the need to assess characteristics of both carbohydrates and secondary metabolites for overall quality evaluation and comparison of ASR and AAR.
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