Evidence map›Paper›PMID 29976401›Full record

ArticleJournal of food and drug analysis2018

Effects of vitamin B-6 supplementation on oxidative stress and inflammatory response in neonatal rats receiving hyperoxia therapy.

Ming-Sheng Lee, Tzu-Cheng Su, Yi-Chia Huang, Rei Cheng Yang, Jun-Kai Kao, Cheng-Han Lee, Jui-Ju Tseng, Chien-Sheng Hsu, Chin-Lin Hsu

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective effects ofFrontiers in pharmacology · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ming-Sheng LeeDepartment of Pediatric Pulmonology and Critical Care, Changhua Christian Children Hospital, Changhua, Taiwan.
Tzu-Cheng SuDepartment of Pathology, Changhua Christian Hospital, Changhua, Taiwan.
Yi-Chia HuangDepartment of Nutrition, Chung Shan Medical University, Taichung, Taiwan.
Rei Cheng YangDepartment of Pediatric Neurology, Changhua Christian Children Hospital, Changhua, Taiwan.
Jun-Kai KaoDepartment of Pediatric Immunology, Changhua Christian Children Hospital, Changhua, Taiwan.
Cheng-Han LeeDepartment of Neonatal Medicine, Changhua Christian Children Hospital, Changhua, Taiwan.
Jui-Ju TsengDepartment of Pediatric Gastrointestinology and Hepatology, Changhua Christian Children Hospital, Changhua, Taiwan.
Chien-Sheng HsuFrontier Molecular Medical Research Center in Children, Changhua Christian Children Hospital, Changhua, Taiwan.
Chin-Lin HsuDepartment of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan.
Changhua Christian Hospital · TWChung Shan Medical University Hospital · TWChung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperoxia is often used in the treatment of neonates. However, protracted use of hyperoxia leads to significant morbidity. The purpose of this study was to evaluate the effects of vitamin B-6 supplementation on oxidative stress and inflammatory responses in neonatal rats undergoing hyperoxia therapy. The study consisted of 2 parts: a survival study and a vitamin B-6 efficacy study for 16 days. Neonatal rats were randomly divided into either the control group, B-6 group (subcutaneously injected with 90 mg/kg/d of pyridoxal 5'-phosphate [PLP]), O

Indexed as

Hyperbaric OxygenationAnimalsAnimals, NewbornCombined Modality TherapyCytokinesDietary SupplementsDisease Models, AnimalFemaleHumansHyperoxiaInfant, NewbornInfant, Newborn, DiseasesLiverLungMaleNeutrophilsCytokinesOxygenSuperoxide DismutaseVitamin B 6HyperoxiaInflammationNeonateOxidative stressVitamin B-6

Identifiers

PMID29976401
PMCPMC9303020
OpenAlexW2791527771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.