Evidence map›Paper›PMID 29976171›Full record

ArticleBMC pediatrics2018

Group B streptococcus late-onset disease,contaminated breast milk and mothers persistently GBS negative: report of 3cases.

Giangiacomo Nicolini, Martina Borellini, Vitaliana Loizzo, Roberta Creti, Luigi Memo, Alberto Berardi

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Breast Milk: A Meal Worth Having.Frontiers in nutrition · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Giangiacomo NicoliniUnità Operativa Complessa di Pediatria e Patologia Neonatale, Ospedale San Martino, Belluno, Italy. gnicolini@gmail.com.ORCID 0000-0003-4259-4540
Martina BorelliniDipartimento Salute della Donna e del Bambino, Scuola di Specializzazione in Pediatria, Università di Padova, Padova, Italy.
Vitaliana LoizzoScuola di Specializzazione in Pediatria, Università degli Studi di Modena e Reggio Emilia, Modena, Italy.
Roberta CretiDipartimento di Malattie Infettive, Istituto Superiore di Sanità, Roma, Italy.
Luigi MemoUnità Operativa Complessa di Pediatria e Patologia Neonatale, Ospedale San Martino, Belluno, Italy.
Alberto BerardiUnità Operativa di Terapia Intensiva Neonatale, Dipartimento Integrato Materno-Infantile, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.
Azienda Ospedaliero-Universitaria di Modena · ITIstituto Superiore di Sanità · ITOspedale Policlinico San Martino · ITUniversity of Modena and Reggio Emilia · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman milk is fundamental for its nutritional properties and to protect newborns, but it is not sterile and can sometime transmit bacteria. Few anecdotal cases suggest that breast milk could be a possible source of group B Streptococcus (GBS) late onset disease, although the pathogenesis is not entirely understood. CASE PRESENTATION: We report 3 cases of GBS late onset disease in full-term newborns. Fresh breast milk cultures yielded GBS, but mothers of neonates had no signs of mastitis and remained persistently GBS negative at rectovaginal site.

conclusionsBreast milk containing group B Streptococcus can be a risk factor for late onset disease. The persistent negative maternal GBS status supports the assumption that newborns, colonised in the throat, could be the initial source of GBS, while the mammary gland could act as a GBS replication site. It is unclear whether a low bacterial load may represent only contamination rather than true milk infection.

Indexed as

Age of OnsetAmpicillinAnti-Bacterial AgentsBreast FeedingFemaleGentamicinsHumansInfant, NewbornMaleMilk, HumanStreptococcal InfectionsStreptococcus agalactiaeAmpicillinAnti-Bacterial AgentsGentamicinsBreastfeedingGroup B streptococcusNewbornSepsis

Identifiers

PMID29976171
PMCPMC6034315
OpenAlexW2836067332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.