Evidence map›Paper›PMID 29976168›Full record

ArticleBMC public health2018

Stress begets stress: the association of adverse childhood experiences with psychological distress in the presence of adult life stress.

Mercy Manyema, Shane A Norris, Linda M Richter

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 154 citations in OpenAlex.

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  6. Effects of HIV and Adverse Childhood Experiences on Neurocognition.Journal of acquired immune deficiency syndromes (1999) · 2026
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  19. Trauma as a mediator of childhood adversity and mental illness in South Africa: A path analysis.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mercy ManyemaDST-NRF Center of Excellence in Human Development, University of the Witwatersrand, 1st Floor School of Public Health Building, Wits Education Campus, 7 York Road, Parktown, Johannesburg, 2193, South Africa. mercy.manyema@gmail.com.ORCID 0000-0001-9123-1952
Shane A NorrisMRC/Wits Developmental Pathways for Health Research Unit, Corner College & Clinic Road, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Linda M RichterDST-NRF Center of Excellence in Human Development, University of the Witwatersrand, 1st Floor School of Public Health Building, Wits Education Campus, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
University of the Witwatersrand · ZA

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundAdverse childhood experiences (ACES) have been linked to poor health and well-being outcomes, including poor mental health such as psychological distress. Both ACEs and psychological distress pose a significant public health burden, particularly in low to middle income countries. Contemporaneous stress events in adulthood may also impact psychological distress. The aims of this study were to describe the prevalence of ACEs and psychological distress and to assess the separate and cumulative effect of ACEs on psychological distress, while accounting for the effect of adult stress.

methodsIn this cross-sectional study, we used retrospectively measured ACEs from a sample of 1223 young adults aged between 22 and 23 years (52% female) from the Birth to Twenty Plus Study. Psychological distress and adult life stress were measured with a six-month recall period. Hierarchical logistic regression was employed to assess the associations between the exposures and outcome.

resultsNearly 90% of the sample reported at least one ACE and 28% reported psychological distress. The median number of ACEs reported was three (range 0-11). After accounting for demographic and socio-economic factors, all ACEs were individually associated with psychological distress except for parental divorce and unemployment. The individual ACEs increased the odds of PD by between 1.42 and 2.79 times. Compared to participants experiencing no ACEs, those experiencing one to five ACEs were three times more likely to report psychological distress (AOR 3.2 95% CI: 1.83-5.63), while participants who experienced six or more ACEs had nearly eight times greater odds of reporting psychological distress (AOR 7.98 95% CI: 4.28-14.91). Interaction analysis showed that in the absence of adult life stress, the effect of low ACEs compared to high ACEs on PD was not significantly different. DISCUSSION AND

conclusionThe prevalence of ACEs in this young adult population is high, similar to other studies in young adult populations. A significant direct association exists between ACEs and psychological distress. Adult life stress seems to be a mediator of this relationship. Interventions targeted at psychological distress should address both early life adversity and contemporary stress.

Indexed as

Adult Survivors of Child Adverse EventsAdverse Childhood ExperiencesCross-Sectional StudiesFemaleHumansMalePrevalenceRetrospective StudiesStress, PsychologicalYoung AdultAdverse childhood experiencesBirth to twenty plusMental healthPsychological distressStressful life eventsYoung adult

Identifiers

PMID29976168
PMCPMC6034311
OpenAlexW2870862977

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.