SynthesisBMC infectious diseases2018
Medical treatment of cystic echinococcosis: systematic review and meta-analysis.
Synthesis in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
84 citing papers in PubMed, 169 citations in OpenAlex.
- Open surgical management of pediatric hepatic hydatid cysts: a retrospective cohort study.Annals of medicine and surgery (2012) · 2026Article
- Postoperative Prophylaxis of Cystic Echinococcosis with Albendazole and Praziquantel: A Retrospective Cohort Study.Biomedicines · 2026Article
- Delayed hyperergic reaction ensuing puncture drainage of an echinococcal cyst in the left hepatic lobe of a six-year-old boy.Infection · 2026Article
- Cystic echinococcosis in Austria 2009-2024: national surveillance and two rare cases of musculoskeletal manifestations including clinical management strategies.BMC musculoskeletal disorders · 2026Article
- Iliopsoas hydatid cyst mimicking an ovarian tumor: a diagnostic pitfall in an endemic setting-a case report.BMC infectious diseases · 2026Article
- Nrf2 regulates angiogenesis in spinal cystic echinococcosis via RTN4.Microbiology spectrum · 2026Article
- Medical, Surgical, and Combined Approaches in Pediatric Hydatid Liver Disease: A Systematic Review.Pediatric reports · 2026Review
- Enhancing hydatid cysts diagnosis utilizing cell-free DNA as a sensitive biomarker forHelminthologia · 2026Article
- Article
- Evaluation of Imatinib and Its Combination With Albendazole AgainstJournal of parasitology research · 2026Article
- Recurrent renal hydatid disease with suspected pelvic seeding: a case report.Journal of surgical case reports · 2026Article
- Preoperative predictive factors of cystobiliary fistulas in liver hydatid cysts: results of a monocentric study.Future science OA · 2025Article
- Hydatid Cyst of the Breast: A Rare Case Report and Literature Review.Clinical case reports · 2025Article
- Challenges in Diagnosing and Managing Ovarian Hydatidosis: A Case Report and Literature Review from Iran.Acta parasitologica · 2025Review
- Surgical decision-making in splenic hydatid cyst management via successful total splenectomy: a case report.Journal of medical case reports · 2025Article
- Article
- Salvia sclarea L. mediated green synthesis of gold nanoparticles (AuNPs) and evaluation of their antibacterial, anticandidal, and scolicidal properties.Scientific reports · 2025Article
- A rare primary occipitocervical hydatid cyst in a 13-year-old girl: a rare case report from Syria.Journal of surgical case reports · 2025Article
- Comparison of the Effectiveness and Complications of PAIR, Open Surgery, and Laparoscopic Surgery in the Treatment of Liver Hydatid Cysts.Medicina (Kaunas, Lithuania) · 2025Article
- Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of this work is to analyse the available data to answer clinical questions regarding medical treatment of CE.
methodsA thorough electronic search of the relevant literature without language restrictions was carried out using PubMed (Medline), Cochrane Central Register of Controlled Trials, BioMed, Database of Abstracts of Reviews of Effects, and Cochrane Plus databases up to February 1, 2017. All descriptive studies reporting an assessment of CE treatment and published in a peer-reviewed journal with available full-text were considered for a qualitative analysis. Randomized controlled trials were included in a quantitative meta-analysis. We used the standard methodological procedures established by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.
resultsWe included 33 studies related to the pharmacological treatment of CE in humans. Of these, 22 studies with levels of evidence 2 to 4 were qualitatively analysed, and 11 randomized controlled trials were quantitatively analysed by meta-analysis.
conclusionsTreatment outcomes are better when surgery or PAIR (Puncture, Aspiration, Injection of protoscolicidal agent and Reaspiration) is combined with benzimidazole drugs given pre- and/or post-operation. Albendazole chemotherapy was found to be the primary pharmacological treatment to consider in the medical management of CE. Nevertheless, combined treatment with albendazole plus praziquantel resulted in higher scolicidal and anti-cyst activity and was more likely to result in cure or improvement relative to albendazole alone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.