Evidence map›Paper›PMID 29975799›Full record

ArticleBritish journal of clinical pharmacology2018

The 'top 100' drugs and classes in England: an updated 'starter formulary' for trainee prescribers.

Selma Audi, Daniel R Burrage, Dagan O Lonsdale, Sarah Pontefract, Jamie J Coleman, Andrew W Hitchings, Emma H Baker

Abstract read
In one paragraph

Article in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Reappraisal of the Effects of L-type CaFunction (Oxford, England) · 2023
    Pooled it
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  14. MEDICATION EXPOSURE AND NEURODEGENERATIVE DISEASE RISK ACROSS NATIONAL BIOBANKS.medRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Selma AudiClinical Pharmacology, Institute of Infection and Immunity, St George's, University of London.
Daniel R BurrageClinical Pharmacology, Institute of Infection and Immunity, St George's, University of London.
Dagan O LonsdaleClinical Pharmacology, Institute of Infection and Immunity, St George's, University of London.ORCID 0000-0003-0838-921X
Sarah PontefractInstitute of Clinical Sciences, University of Birmingham.
Jamie J ColemanInstitute of Clinical Sciences, University of Birmingham.
Andrew W HitchingsClinical Pharmacology, Institute of Medical and Biomedical Education, St George's, University of London.ORCID 0000-0002-2802-1466
Emma H BakerClinical Pharmacology, Institute of Infection and Immunity, St George's, University of London.ORCID 0000-0002-0871-3721

Funding

Department of Health DRF-2016-09-088
6 · The paper itself

Abstract

aimsPrescribing is a complex skill required of doctors and, increasingly, other healthcare professionals. Use of a personal formulary can help to develop this skill. In 2006-9, we developed a core list of the 100 most commonly prescribed drugs. Our aim in the present study was to update this 'starter formulary' to ensure its continued relevance for prescriber training.

methodsWe analysed large contemporary primary and secondary care datasets to identify the most frequently prescribed medicinal products. Items were classified into natural groups, broadly following their British National Formulary classification. The resulting drug groups were included in the core list if they comprised ≥0.1% prescriptions in both settings or ≥0.2-0.3% prescriptions in one setting. Drugs from emergency guidelines that did not qualify by prescribing frequency completed the list.

resultsOver 1 billion primary care items and approximately 1.8 million secondary care prescriptions were analysed. The updated list comprises 81 drug groups commonly prescribed in both settings; six from primary care; seven from secondary care; and six from emergency guidelines. Eighty-eight per cent of the formulary was unchanged. Notable changes include entry of newer anti-epileptics and dipeptidyl peptidase-4 inhibitors and exit of phenytoin and thiazolidinediones.

conclusionsThe relative stability of the core drug list over 9 years and the current update ensure that learning based on this list remains relevant to practice. Trainee prescribers may be encouraged to use this 'starter formulary' to develop a sound basis of prescribing knowledge and skills that they can subsequently apply more widely.

Indexed as

Formularies as TopicClinical CompetenceDrug PrescriptionsEnglandHumansPractice Guidelines as TopicPractice Patterns, Physicians'Prescription DrugsPrimary Health CareSecondary Health CarePrescription Drugsgeneral medicinemedical educationpharmacoepidemiology

Identifiers

PMID29975799
PMCPMC6177714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.