ArticlePloS one2018
Influence of seasonal variation on in vitro fertilization success.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Association between season and pregnancy outcomes in fresh embryo transfer cycles: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Breed and Season: Key Determinants of Efficiency in Large-Scale CommercialAnimals : an open access journal from MDPI · 2025Article
- Association between meteorological season and embryo quality in the era of morphokinetics.JBRA assisted reproduction · 2025Article
- The impact of seasonal variations on IVF pregnancy outcomes: a retrospective cohort study in Jinan, China.Frontiers in medicine · 2025Article
- The association between season and meteorological factors on clinical outcomes after fresh embryo transfer: a cohort study from Central Plains, China.Frontiers in endocrinology · 2025Article
- Seasonality's Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis.Journal of pharmacy & bioallied sciences · 2024Article
- Seasonal fluctuation of in vitro fertilization encounters in the United States.Journal of assisted reproduction and genetics · 2023Article
- Season and temperature do not affect cumulative live birth rate and time to live birth inFrontiers in endocrinology · 2023Article
- Influence of climatic conditions in the mesothermal climate area on pregnancies following elective fresh single blastocyst transfer.Journal of assisted reproduction and genetics · 2022Article
- Summer is not associated with higher live birth rates in fresh IVF/ICSI cycles: a population-based nationwide registry study.Human reproduction open · 2022Article
- Objective sleep duration and timing predicts completion of in vitro fertilization cycle.Journal of assisted reproduction and genetics · 2021Article
- Seasonal variation, temperature, day length, and IVF outcomes from fresh cycles.Journal of assisted reproduction and genetics · 2020Article
- Seasonal patterns in fecundability in North America and Denmark: a preconception cohort study.Human reproduction (Oxford, England) · 2020Article
- Association betweenObstetrics & gynecology science · 2020Article
- Seasonal variability does not impact in vitro fertilization success.Scientific reports · 2019Article
- Seasonal Influence on Assisted Reproductive Technology Outcomes: A Retrospective Analysis of 1409 Cycles.Journal of human reproductive sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the influence of seasonal variation on in vitro fertilization (IVF) outcome in a large cohort population. METHODS & MATERIALS: A total of 5,765 IVF cycles conducted in Sheba medical center between 2013 and 2016 were retrospectively analyzed. The treatment cycles included 4214 ovarian stimulation and ovum pick up (OPU) cycles of which 3020 resulted in fresh embryo transfer and 1551 vitrified- warmed cycles of which1400 resulted in warmed embryo transfer. Cycles were assigned to seasons according to the date of OPU for fresh embryo transfer cycles or according to the date of embryo warming for vitrified warmed embryo transfer cycles.
resultsThere were no statistically significant differences between the calendar months or seasons concerning the number of oocytes retrieved or fertilization rate in the fresh cycles. Throughout the 4 years of the study, the monthly clinical pregnancy rate fluctuated between 18.2% and 27.9% per fresh embryo transfer (mean 23.3%) and between 17.7% and 29.4% per vitrified warmed embryo transfer (mean 23%). These fluctuations did not follow any specific seasonal pattern.
conclusionsOur study did not demonstrate any significant influence of the calendar months or seasons on the clinical pregnancy rates of fresh or vitrified warmed embryo transfers. It might be speculated that the complete pharmaceutical control of the ovarian and endometrial function, as well as the homogeneous treatments, procedures and laboratory equipment used during the study period have lowered the influence of seasonal effect on IVF treatment outcome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.