Evidence map›Paper›PMID 29975593›Full record

ReviewPathogens and global health2018

Considerations for the governance of gene drive organisms.

Larisa Rudenko, Megan J Palmer, Kenneth Oye

Abstract readReview
In one paragraph

Review in Pathogens and global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Design biology and mind-body health.Journal, genetic engineering & biotechnology · 2025
    Review
  3. Is Gene Drive Research Losing Traction?The American journal of tropical medicine and hygiene · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Making gene drive biodegradable.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Larisa Rudenkoa Visiting Scholar, Program on Emerging Technologies , Massachusetts Institute of Technology , Cambridge , MA , USA.ORCID 0000-0001-6074-8676
Megan J Palmerb Center for International Security and Cooperation , Stanford University , Stanford , CA , USA.ORCID 0000-0001-8310-2325
Kenneth Oyec Program on Emerging Technologies , Massachusetts Institute of Technology , Cambridge , MA , USA.ORCID 0000-0002-9811-8415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Governance is a broader and more flexible concept than statute-driven regulations as it incorporates components outside the latter's remit. Considerations of governance are critical in the development of emerging biotechnologies such as gene drive organisms. These have been proposed or are being developed to address public and environmental health issues not addressed easily by conventional means. Here, we consider how the concept of governance differs from statute-driven regulation with reference to the role each may play in the development of gene drive organisms. First, we discuss existing statute-based regulatory systems. Second, we consider whether novel risks or different concerns derive from gene drive organisms, concentrating on characteristics that contribute to public health or environmental risk and uncertainties that may affect risk perceptions. Third, we consider public engagement, outlining how existing statute-driven regulatory systems and other governance mechanisms may provide opportunities for constructive interactions. Finally, we provide some observations that may help address science- and values-based concerns in a governance space larger than that of statute-driven regulatory systems.

Indexed as

Health PolicyOrganisms, Genetically ModifiedAnimalsGene Drive TechnologyHumansPlantsGene drivesgovernancepublic engagementregulationriskrisk management

Identifiers

PMID29975593
PMCPMC7025691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.