Evidence map›Paper›PMID 29975157›Full record

ArticleMolecular biology of the cell2018

Analysis of the contribution of phosphoinositides to medial septation in fission yeast highlights the importance of PI(4,5)P

Chloe E Snider, Alaina H Willet, HannahSofia T Brown, Kathleen L Gould

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Fission yeast Opy1 is an endogenous PI(4,5)PJournal of cell science · 2020
    Article
  8. Article
  9. Plasma Membrane MCC/Eisosome Domains Promote Stress Resistance in Fungi.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chloe E SniderDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232.
Alaina H WilletDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232.
HannahSofia T BrownDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232.
Kathleen L GouldDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232.
Vanderbilt University · USDuke University · US

Funding

TRAINING PROGRAM IN CELLULAR, BIOCHEMICAL, &MOLECULAR ST32GM008554 · NIGMS · VANDERBILT UNIVERSITY · PI PATTON, JAMES G. · 1995 to 2020
$7.4M
Regulation of CytokinesisR01GM101035 · NIGMS · VANDERBILT UNIVERSITY · PI GOULD, KATHLEEN L · 2012 to 2018
$2.8M
NIGMS NIH HHS R01 GM101035NIGMS NIH HHS T32 GM008554
6 · The paper itself

Abstract

In Schizosaccharomyces pombe, loss of the plasma membrane PI4-kinase scaffold Efr3 leads to sliding of the cytokinetic ring (CR) away from the cell center during anaphase, implicating phosphoinositides (PIPs) in CR anchoring. However, whether other PIP regulators contribute to CR anchoring has not been investigated. Here we report that mutants of other PIP kinases and their regulators divide with off-center septa, similar to efr3∆. Using new biosensors for S. pombe PIPs, we confirm that these mutants have disrupted PIP composition. We extend a previous finding that a mutant known to decrease PI(3,5)P

Indexed as

ActinsAnaphaseCell Cycle ProteinsCell DivisionCell NucleusCytokinesisCytoplasmMitosisPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsActinsCell Cycle ProteinsEFR3 protein, S cerevisiaePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID29975157
PMCPMC6249800
OpenAlexW2868682529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.