Evidence map›Paper›PMID 29974893›Full record

ArticleJournal of cell biology and histology2018

Endothelial Cells May Have Tissue-Specific Origins.

Kristina I Boström, Jiayi Yao, Xiuju Wu, Yucheng Yao

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of cell biology and histology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Physiological and Pathological Remodeling of Cerebral Microvessels.International journal of molecular sciences · 2022
    Review
  2. Review
  3. Novel, Emerging Chip Models of the Blood-Brain Barrier and Future Directions.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. The potential role of 3D-bioprinting in xenotransplantation.Current opinion in organ transplantation · 2019
    Review
  8. Article
  9. Vascular Niche in Lung Alveolar Development, Homeostasis, and Regeneration.Frontiers in bioengineering and biotechnology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristina I BoströmDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, U.S.A.
Jiayi YaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, U.S.A.
Xiuju WuDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, U.S.A.
Yucheng YaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, U.S.A.

Funding

ULTRASTRUCTURE OF THE INTIMA IN EARLY LESION FORMATIONP01HL030568 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FOGELMAN, ALAN M · 1985 to 2019
$55.2M
Molecular Mechanisms of MGP; Role in AVMsR01HL081397 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOSTROM, KRISTINA I · 2006 to 2025
$7.7M
BMP and Notch Crosstalk in Cerebral Arteriovenous MalformationsR01NS079353 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2012 to 2026
$5.3M
Switch of Osteogenesis in Vascular CalcificationR01HL139675 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2018 to 2026
$3.6M
Role of The Endothelium In Vascular CalcificationR01HL112839 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOSTROM, KRISTINA I · 2013 to 2016
$1.5M
NHLBI NIH HHS P01 HL030568NHLBI NIH HHS R01 HL081397NHLBI NIH HHS R01 HL112839NHLBI NIH HHS R01 HL139675NINDS NIH HHS R01 NS079353
6 · The paper itself

Abstract

Endothelial heterogeneity reflects many functions performed by endothelial cells (ECs) in various tissues. However, the origin of this heterogeneity is unclear. Here, we report that tissue-specific ECs in lungs, brain and liver co-expressed the lineage markers of their coordinating tissue-specific cells at very early stages. Specifically, we found that the pulmonary EC population was significantly suppressed after pulmonary epithelial-specific (

Indexed as

DifferentiationEndothelial cellsHeterogeneityTissue-specific

Identifiers

PMID29974893
PMCPMC6028056

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.