Evidence map›Paper›PMID 29974859›Full record

ArticleDevelopmental cell2018

"Rho"ing a Cellular Boat with Rearward Membrane Flow.

George R R Bell, Sean R Collins

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

George R R BellDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA 95616, USA.
Sean R CollinsDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA 95616, USA. Electronic address: srcollins@ucdavis.edu.

Funding

Rewiring Control of Leukocyte Motility for Therapeutic ApplicationDP2HD094656 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COLLINS, SEAN RYAN · 2017 to 2017
$2.4M
NICHD NIH HHS DP2 HD094656
6 · The paper itself

Abstract

The physicist Edward Purcell wrote in 1977 about mechanisms that cells could use to propel themselves in a low Reynolds number environment. Reporting in Developmental Cell, O'Neill et al. (2018) provide direct evidence for one of these mechanisms by optogenetically driving the migration of cells suspended in liquid through RhoA activation.

Indexed as

rhoA GTP-Binding ProteinCell Movementrho-Associated KinasesrhoA GTP-Binding Proteinrho-Associated Kinases

Identifiers

PMID29974859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.