Evidence map›Paper›PMID 29974141›Full record

ArticleInternational urogynecology journal2019

The proportion of women with central sensitivity syndrome in gynecology outpatient clinics (GOPDs).

Monika Vij, Anthony Davies, Anu Dua, Robert Freeman

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Article in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Monika VijDerriford Hospital, Plymouth, UK. monikavij72@yahoo.co.in.ORCID http://orcid.org/0000-0001-6805-7538
Anthony DaviesDerriford Hospital, Plymouth, UK.
Anu DuaDerriford Hospital, Plymouth, UK.
Robert FreemanDerriford Hospital, Plymouth, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisPatients in gynecology outpatient clinics (GOPDs) may present with symptoms that do not correlate well with the observed pathology and are usually labelled as having a functional disorder or medically unexplained symptoms (MUS). Underlying central sensitivity syndrome (CSS) with central sensitization (CS) as a potential mechanism may be responsible for some of their symptoms. The aim of this study is to identify the proportion of women with central sensitivity syndrome attending GOPDs.

methodsThis was a prospective study. All women attending a GOPD included in the study were asked to complete a validated Central Sensitization Inventory (CSI). The responses were graded on a Likert scale from 0 (never) to 4 (always). The total score ranges from 0 to 100. For screening purposes, a single CSI cutoff score of 40 was used to identify the group of women who may have central sensitization syndrome.

resultsThree hundred twenty-six women participated in the study. Overall, 123 (37%) women achieved a score above 40. This could be interpreted as these patients having increased risk of underlying central sensitization. Of these, 43 had a previously confirmed diagnosis of migraine, 55 (44%) depression, 39 (31.7%) anxiety, 11 fibromyalgia (FM), 34 irritable bowel syndrome (IBS) and 16 chronic fatigue syndrome (CFS/ME).

conclusionsManaging patients and their expectations in gynecological outpatient departments when symptoms are inconsistent with observable pathological findings is challenging. This is further complicated when patients have a concomitant central sensitivity syndrome, which can also influence the surgical outcome. Identifying these patients is a key factor for appropriate management.

Indexed as

Central Nervous System SensitizationAmbulatory CareAnxietyComorbidityDepressionFatigue Syndrome, ChronicFemaleFibromyalgiaGenital Diseases, FemaleGynecologyHumansIrritable Bowel SyndromeMigraine DisordersNervous System DiseasesPelvic Organ ProlapsePrevalenceCentral sensitivity syndromeCentral sensitizationGynecology outpatient clinicPelvic organ prolapse

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.