Evidence map›Paper›PMID 29974138›Full record

ArticleInternational urogynecology journal2019

Technique development and measurement of cross-sectional area of the pubovisceral muscle on MRI scans of living women.

Mariana Masteling, James A Ashton-Miller, John O L DeLancey

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05800678 (Comparison of Cross-sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05800678 completednot on this mapstarted 2021, after this paper: background citation

Comparison of Cross-sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

TypeobservationalSponsorInstitute for the Care of Mother and Child, Prague, Czech RepublicRan2021 to 2023Enrolled80ConditionsPelvic Floor Disorders
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mariana MastelingDepartment of Mechanical Engineering, University of Michigan, 2350 Hayward St, Ann Arbor, MI, 48109, USA. mastelin@umich.edu.ORCID 0000-0001-7012-6950
James A Ashton-MillerDepartment of Mechanical Engineering, University of Michigan, 2350 Hayward St, Ann Arbor, MI, 48109, USA.
John O L DeLanceyDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, 48109, USA.
University of Michigan · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Which pelvic floor defects cause stress incontinence?P50HD044406 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2002 to 2017
$17.1M
Mechanisms of anterior vaginal wall support failureR01HD038665 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2000 to 2014
$3.8M
NIA NIH HHS P30 AG024824NICHD NIH HHS P50 HD044406NICHD NIH HHS R01 HD038665NIH HHS HD R01 38665NIH HHS P50 HD044406-07
6 · The paper itself

Abstract

introduction and hypothesisMeasurements of the anatomic cross-sectional area (CSA) of the pubovisceral muscle (PVM) in women are confounded by the difficulty of separating the muscle from the adjacent puborectal (PRM) and iliococcygeal (ICM) muscles when visualized in a plane orthogonal to the fiber direction. We tested the hypothesis that it might be possible to measure the PVM CSA within a defined region of interest based on magnetic resonance images (MRI).

methodsMRI scans of 11 women with unilateral PVM tears and seven primiparous women with intact muscles following elective C-section were used to identify the PVM injury zone defined by the mean location of its boundaries with the adjacent intact PRM and ICM from existing anatomic reference points using 3D Slicer and ImageJ software. Then, from the 15 or more 2-mm transverse slices available, the slice with the maximum anatomic CSA of the left and right PVM was found in 24 primiparous women with bilaterally intact muscles who had delivered via C-section.

resultsMean [± standard deviation (SD)] of the maximum left or right PVM cross-section areas for the 24 women, measured by two different raters, was 1.25 ± 0.29 cm

conclusionsIt is possible to use MRI to identify the volume of interest with the maximum anatomic cross section of the PVM belly while minimizing the inadvertent inclusion of adjacent PRM or ICM in that measurement.

Indexed as

Magnetic Resonance ImagingAdultBody Weights and MeasuresFemaleHumansMiddle AgedPelvic FloorVisceraCross-sectional areaMRIPubovisceral muscle

Identifiers

PMID29974138
PMCPMC6320718
OpenAlexW2832997743

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.