ArticleJournal of cancer epidemiology2018
Effects of Different Treatment Strategies and Tumor Stage on Survival of Patients with Advanced Laryngeal Carcinoma: A 15-Year Cohort Study.
Article in Journal of cancer epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Leveraging vision transformer for histological grade prediction in laryngeal and hypopharyngeal squamous cell carcinoma: a large-scale multicenter study.Neuroradiology · 2026Article
- A retrospective study of laryngeal squamous cell carcinoma and the significance of the PIK3CA mutation for survival.Molecular and clinical oncology · 2025Article
- Machine learning in personalized laryngeal cancer management: insights into clinical characteristics, therapeutic options, and survival predictions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Chemoradiotherapy vs radiotherapy for non-surgical locally advanced laryngeal squamous cell carcinoma patients: a propensity score-matched study and practical nomogram construction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Survival Outcomes in T3 Laryngeal Cancers: Primary Total Laryngectomy vs. Concurrent Chemoradiation or Radiation Therapy-A Meta-Analysis.Biomedicines · 2023Review
- Outcomes of organ preservation treatment in advanced laryngeal carcinoma: A retrospective analysis from a single institution.Molecular and clinical oncology · 2023Article
- Investigation of the affective factors on the survival rate of patients with laryngeal cancer using Cox proportional hazards and Lin -Ying's additive hazards models.Medical journal of the Islamic Republic of Iran · 2021Article
- Time between Diagnosis and Treatment of Hypopharynx and Larynx Cancer: Are Longer Delays Associated with Higher Discrepancy between Clinical and Pathological Staging?International archives of otorhinolaryngology · 2021Article
- Survival prediction and treatment strategies for patients with advanced laryngeal carcinoma: a population-based study.International journal of clinical oncology · 2020Article
- Statin use associated with improved overall and cancer specific survival in patients with head and neck cancer.Oral oncology · 2019Article
- Impact ofCancer genomics & proteomicsArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaryngeal cancer is the second most common cancer in the head and neck. Since laryngeal cancer management is a complex process, there is still no standard strategy to treat this disease in order to increase the survival rate of the patients especially among those with advanced form of the disease.
methodsA cohort study was undertaken to analyze factors predicting survival of the patients in advanced stage laryngeal cancer in the Southern Iran among all patients newly diagnosed with laryngeal cancer between 2000 and 2015.
resultsData of a total number of 415 patients who have had been diagnosed with advanced laryngeal cancer during this period was used for analysis. The patients' 1-, 3-, 5-, and 10-year survival rates were 81%, 62%, 53%, and 38%, respectively. Multivariable Cox regression analyses indicated a significant relationship between patients' survival and age at diagnosis (
conclusionThis study showed that the survival of patients depends on several factors, among which, treatment strategy is the most important. Combination of total laryngectomy plus chemoradiation provides superior local control and better survival compared to either radiotherapy or chemoradiation in patients with advanced laryngeal cancer.
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