Evidence map›Paper›PMID 29973921›Full record

ArticleFrontiers in microbiology2018

Genome Mining of the Marine Actinomycete

Xiao-Na Xu, Liang-Yu Chen, Chao Chen, Ya-Jie Tang, Feng-Wu Bai, Chun Su, Xin-Qing Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. In Silico Analysis and Biochemical Characterization ofJournal of microbiology and biotechnology · 2024
    Article
  3. Marine-DerivedMicroorganisms · 2023
    Article
  4. Article
  5. Complete Genome Sequence of the Marine-Derived BacteriumMicrobiology resource announcements · 2021
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Frontiers in microbiology · 2019
    Article
  12. Comparative Genomics of Marine Sponge-DerivedFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Xiao-Na XuSchool of Life Sciences and Biotechnology, Dalian University of Technology, Dalian, China.
Liang-Yu ChenSchool of Life Sciences and Biotechnology, Dalian University of Technology, Dalian, China.
Chao ChenCollege of Life Science, Dalian Minzu University, Dalian, China.
Ya-Jie TangKey Laboratory of Fermentation Engineering, Ministry of Education - Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, China.
Feng-Wu BaiState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Chun SuKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, College of Life Sciences, Shaanxi Normal University, Xi'an, China.
Xin-Qing ZhaoState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Jiao Tong University · CNDalian Minzu University · CNDalian University · CNDalian University of Technology · CNHubei University of Technology · CNShaanxi Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine actinobacteria are potential producers of various secondary metabolites with diverse bioactivities. Among various bioactive compounds, anti-complement agents have received great interest for drug discovery to treat numerous diseases caused by inappropriate activation of the human complement system. However, marine streptomycetes producing anti-complement agents are still poorly explored. In this study, a marine-derived strain

Indexed as

anti-complement activitygenome miningmarine streptomycetessecondary metabolitestunicamycin

Identifiers

PMID29973921
PMCPMC6019454
OpenAlexW2806945283

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.