Evidence map›Paper›PMID 29973869›Full record

ArticleFrontiers in molecular neuroscience2018

Endocannabinoid Signaling at Hypothalamic Steroidogenic Factor-1/Proopiomelanocortin Synapses Is Sex- and Diet-Sensitive.

Carolina Fabelo, Jennifer Hernandez, Rachel Chang, Sakara Seng, Natalia Alicea, Sharon Tian, Kristie Conde, Edward J Wagner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Endocannabinoid System and Metabolism: The Influences of Sex.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
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  13. Review
  14. CB1Rs in VMH neurons regulate glucose homeostasis but not body weight.American journal of physiology. Endocrinology and metabolism · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Carolina FabeloDepartment of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Jennifer HernandezGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Rachel ChangGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Sakara SengDepartment of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Natalia AliceaCollege of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, United States.
Sharon TianDepartment of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Kristie CondeDepartment of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Edward J WagnerDepartment of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Western University of Health Sciences · US

Funding

Sex Differences in the Cannabioid Regulation of Energy HomeostasisR15DA024314 · NIDA · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI WAGNER, EDWARD J · 2008 to 2020
$1.5M
NIDA NIH HHS R15 DA024314
6 · The paper itself

Abstract

We tested the hypotheses that steroidogenic factor (SF)-1 neurons in the hypothalamic ventromedial nucleus (VMN) provide sexually disparate, endocannabinoid (EC)- and diet-sensitive glutamatergic input onto proopiomelanocortin (POMC) neurons. Electrophysiological recordings were performed in hypothalamic slices from intact and castrated guinea pigs, along with

Indexed as

endocannabinoidsestradiolinsulinobesityproopiomelanocortinsex differencessteroidogenic factor-1testosterone

Identifiers

PMID29973869
PMCPMC6020785
OpenAlexW2806854221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.