Evidence map›Paper›PMID 29973680›Full record

ReviewNature reviews. Genetics2018

Population genomics of bacterial host adaptation.

Samuel K Sheppard, David S Guttman, J Ross Fitzgerald

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed.

  1. AcceleratingProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  3. Review
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  7. Article
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  12. From colonisation to chronicity: adaptation ofMicrobiology (Reading, England) · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Host-Driven Genetic Diversity ofTransboundary and emerging diseases · 2026
    Article
  18. Article
  19. Article
  20. Genomic Markers Distinguishing Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2025
    Article

101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samuel K SheppardMilner Centre for Evolution, Department of Biology & Biotechnology, University of Bath, Claverton Down, Bath, UK.
David S GuttmanDepartment of Cell & Systems Biology, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-8479-3869
J Ross FitzgeraldThe Roslin Institute, University of Edinburgh, Easter Bush Campus, Edinburgh, UK. Ross.Fitzgerald@ed.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/I013873/1Medical Research Council G0801929Medical Research Council MR/L015080/1Medical Research Council MR/N02995X/1Wellcome Trust 201531/Z/16/Z
6 · The paper itself

Abstract

Some bacteria can transfer to new host species, and this poses a risk to human health. Indeed, an estimated 60% of all human pathogens have originated from other animal species. Similarly, human-to-animal transitions are recognized as a major threat to sustainable livestock production, and emerging pathogens impose an increasing burden on crop yield and global food security. Recent advances in high-throughput sequencing technologies have enabled comparative genomic analyses of bacterial populations from multiple hosts. Such studies are providing new insights into the evolutionary processes that underpin the establishment of bacteria in new host niches. A better understanding of the genetic and mechanistic basis for bacterial host adaptation may reveal novel targets for controlling infection or inform the design of approaches to limit the emergence of new pathogens.

Indexed as

BacteriaBacterial Physiological PhenomenaBiological EvolutionAdaptation, PhysiologicalAnimalsHost-Pathogen InteractionsHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.