Evidence map›Paper›PMID 29973570›Full record

ArticleNutrients2018

Are Total and Individual Dietary Lignans Related to Cardiovascular Disease and Its Risk Factors in Postmenopausal Women? A Nationwide Study.

Anna Maria Witkowska, Anna Waśkiewicz, Małgorzata Elżbieta Zujko, Danuta Szcześniewska, Urszula Stepaniak, Andrzej Pająk, Wojciech Drygas

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Lignan exposure: a worldwide perspective.European journal of nutrition · 2022
    Review
  9. Origin of Wine Lignans.Plant foods for human nutrition (Dordrecht, Netherlands) · 2021
    Article
  10. Review
  11. Review
  12. Review
  13. Oxidative Transformations of Lignans.Molecules (Basel, Switzerland) · 2019
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Anna Maria WitkowskaDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna 37, 15-295 Bialystok, Poland. witam@umb.edu.pl.ORCID 0000-0002-0092-3409
Anna WaśkiewiczDepartment of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology, Alpejska 42, 04-628 Warsaw, Poland. awaskiewicz@ikard.pl.
Małgorzata Elżbieta ZujkoDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna 37, 15-295 Bialystok, Poland. malgorzata.zujko@umb.edu.pl.ORCID 0000-0002-0410-3539
Danuta SzcześniewskaDepartment of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology, Alpejska 42, 04-628 Warsaw, Poland. dszczesniewska@ikard.pl.
Urszula StepaniakDepartment of Epidemiology and Population Studies, Faculty of Health Sciences, Institute of Public Health, Jagiellonian University Medical College, Grzegórzecka 20, 31-531 Krakow, Poland. urszula.stepaniak@uj.edu.pl.
Andrzej PająkDepartment of Epidemiology and Population Studies, Faculty of Health Sciences, Institute of Public Health, Jagiellonian University Medical College, Grzegórzecka 20, 31-531 Krakow, Poland. andrzej.pajak@uj.edu.pl.
Wojciech DrygasDepartment of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology, Alpejska 42, 04-628 Warsaw, Poland. wdrygas@ikard.pl.
Institute of Cardiology · PLJagiellonian University · PLMedical University of Białystok · PLMedical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study objectives were to examine total and individual lignan intakes and their dietary sources in postmenopausal Polish women and to investigate the relationship between lignan intake and the prevalence of cardiovascular disease (CVD), hypertension, hypercholesterolemia and central obesity. A total of 2599 postmenopausal women, participants of the Multi-centre National Population Health Examination Surveys (WOBASZ and WOBASZ II) were selected. Of them, 916 had a history of CVD. Nutritional data were collected using a single 24-h dietary recall. Data on lignan content in food, i.e., lariciresinol (LARI), matairesinol (MAT), pinoresinol (PINO) and secoisolariciresinol (SECO), were collected from the available lignan databases. In postmenopausal women, total and individual lignan intakes (SECO, PINO, MAT) were not associated with the prevalence of CVD and its risk factors. The intake of LARI was linked by 30% to the reduced odds for hypercholestrolemia. This study reinforces the existing concept that dietary total lignans are not associated with the prevalence of CVD, and provides further evidence that they are not linked to CVD risk factors such as hypertension, hypercholesterolemia and central obesity. However, the intake of LARI should be taken into consideration in further studies with regard to its potentially beneficial effect in hypercholesterolemia.

Indexed as

DietPostmenopauseAgedAge FactorsCardiovascular DiseasesCross-Sectional StudiesDiet SurveysFemaleHumansHypercholesterolemiaHypertensionLignansLogistic ModelsMiddle AgedObesity, AbdominalOdds RatioLignanscardiovascular diseasecentral obesityhypercholesterolemiahypertensionlariciresinollignanpostmenopausal

Identifiers

PMID29973570
PMCPMC6073341
OpenAlexW2809933908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.