Evidence map›Paper›PMID 29973256›Full record

ArticleTrials2018

The caries-arresting effect of incorporating functionalized tricalcium phosphate into fluoride varnish applied following application of silver nitrate solution in preschool children: study protocol for a randomized, double-blind clinical trial.

Kitty Jieyi Chen, Sherry Shiqian Gao, Duangporn Duangthip, Edward Chin Man Lo, Chun Hung Chu

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03423797 (Effectiveness of Biannual Application of Silver Nitrate Solution Followed by Sodium Fluoride Varnish With or Without Functionalized Tricalcium Phosphate in Arresting Caries in Preschool Children), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03423797 phase3completednot on this map

Effectiveness of Biannual Application of Silver Nitrate Solution Followed by Sodium Fluoride Varnish With or Without Functionalized Tricalcium Phosphate in Arresting Caries in Preschool Children

TypeinterventionalSponsorThe University of Hong KongRan2017 to 2020Enrolled408ConditionsEarly Childhood CariesArms25% AgNO3 solution followed by 5% NaF, 25% AgNO3 solution followed by 5% NaF with fTCP
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kitty Jieyi ChenFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Pokfulam, China.
Sherry Shiqian GaoFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Pokfulam, China.
Duangporn DuangthipFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Pokfulam, China. dduang@hku.hk.ORCID http://orcid.org/0000-0002-3819-3560
Edward Chin Man LoFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Pokfulam, China.
Chun Hung ChuFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Pokfulam, China.
University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental caries in primary teeth is prevalent, affecting millions of children around the world. Functionalized tricalcium phosphate (fTCP) has been incorporated into sodium fluoride (NaF) varnish to enhance the remineralization process. NaF varnish with the adjunctive application of silver nitrate (AgNO METHODS/

designThis is a randomized, double-blind controlled trial. The null hypothesis tested is that no difference exists between the effectiveness of a 25% AgNO DISCUSSION: The effectiveness of the topical application of a 25% AgNO

trial registrationClinicalTrials.gov (U.S.): NCT03423797 on 6 February 2018.

Indexed as

Calcium PhosphatesChild, PreschoolDental CariesDouble-Blind MethodHumansRandomized Controlled Trials as TopicSample SizeSilver NitrateSodium FluorideSolutionsCalcium PhosphatesSilver NitrateSodium FluorideSolutionstricalcium phosphateChildrenDental cariesFluoride varnishFunctionalized tricalcium phosphateSilver nitrate

Identifiers

PMID29973256
PMCPMC6032524
OpenAlexW2810181853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.