Evidence map›Paper›PMID 29973239›Full record

SynthesisJournal of orthopaedic surgery and research2018

Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review.

Ya-Zhou Zhang, Xu-Yang Cao, Xi-Cheng Li, Jia Chen, Yue-Yuan Zhao, Zhi Tian, Wang Zheng

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Evidence-Supported HBO Therapy in Femoral Head Necrosis: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Review
  4. Stem Cells From Human Exfoliated Deciduous Teeth as a Potent Cell Therapy for Radiation-Induced Osteonecrosis Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
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  14. Article
  15. Review
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  17. Review
  18. Review
  19. Trochanteric osteotomy for acetabular fracture fixation: a case series and literature review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Zhou ZhangDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.
Xu-Yang CaoDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.
Xi-Cheng LiDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China. zccsfh@163.com.ORCID http://orcid.org/0000-0003-0452-5691
Jia ChenDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.
Yue-Yuan ZhaoDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.
Zhi TianDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.
Wang ZhengDepartment of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head.

methodsBy searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). Summary receiver operating characteristic (SROC) analyses were performed for meniscal tears.

resultsForty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. The global sensitivity and specificity of MRI in early osteonecrosis of the femoral head were 93.0% (95% CI 92.0-94.0%) and 91.0% (95% CI 89.0%-93.0%), respectively. The global positive likelihood ratio and global negative likelihood ratio of MRI in early osteonecrosis of the femoral head were 2.74 (95% CI 1.98-3.79) and 0.18 (95% CI 0.14-0.23), respectively. The global DOR was 27.27 (95% CI 17.02-43.67), and the area under the SROC was 93.38% (95% CI 90.87%-95.89%).

conclusionsThis review provides a systematic review and meta-analysis to evaluate the diagnostic accuracy of MRI in early osteonecrosis of the femoral head. Moderate to strong evidence indicated that MRI appears to be significantly associated with higher diagnostic accuracy for early osteonecrosis of the femoral head.

Indexed as

Femur Head NecrosisHumansMagnetic Resonance ImagingReproducibility of ResultsSensitivity and SpecificityDiagnostic accuracyEarly osteonecrosis of the femoral headMagnetic resonance imagingMeta-analysis

Identifiers

PMID29973239
PMCPMC6031173

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.