Evidence map›Paper›PMID 29973229›Full record

Trial reportReproductive health2018

mHealth intervention to improve the continuum of maternal and perinatal care in rural Guatemala: a pragmatic, randomized controlled feasibility trial.

Boris Martinez, Enma Coyote Ixen, Rachel Hall-Clifford, Michel Juarez, Ann C Miller, Aaron Francis, Camilo E Valderrama, Lisa Stroux, Gari D Clifford, Peter Rohloff

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Reproductive health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02348840 (Mobile Health Intervention to Improve Perinatal Continuum of Care in Guatemala), which is not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02348840 nacompletednot on this map

Mobile Health Intervention to Improve Perinatal Continuum of Care in Guatemala

TypeinterventionalSponsorEmory UniversityRan2015 to 2018Enrolled843ConditionsPregnancy, Prenatal CareArmsmHealth
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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  5. The FemTech revolution: Unlocking the potential of new technology for optimizing pregnancy outcomes in low- and middle-income countries and remote areas.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Boris MartinezWuqu' Kawoq | Maya Health Alliance, 2a. Calle 5-43 Zona 1, Santiago Sacatepéquez, Guatemala.
Enma Coyote IxenWuqu' Kawoq | Maya Health Alliance, 2a. Calle 5-43 Zona 1, Santiago Sacatepéquez, Guatemala.
Rachel Hall-CliffordDepartments of Sociology and Anthropology and Public Health, Agnes Scott College, Decatur, GA, USA.
Michel JuarezWuqu' Kawoq | Maya Health Alliance, 2a. Calle 5-43 Zona 1, Santiago Sacatepéquez, Guatemala.
Ann C MillerDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Aaron FrancisDepartment of Biomedical Informatics, Emory University, Atlanta, GA, USA.
Camilo E ValderramaDepartment of Biomedical Informatics, Emory University, Atlanta, GA, USA.
Lisa StrouxInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Gari D CliffordDepartment of Biomedical Informatics, Emory University, Atlanta, GA, USA.
Peter RohloffWuqu' Kawoq | Maya Health Alliance, 2a. Calle 5-43 Zona 1, Santiago Sacatepéquez, Guatemala. peter@wuqukawoq.org.ORCID http://orcid.org/0000-0001-7274-8315
Emory University · USProbigua · GTAgnes Scott College · USBrigham and Women's Hospital · USGeorgia Institute of Technology · USHarvard University · USSaint Peter's University Hospital · USUniversity of Oxford · GB

Funding

Mobile Health Intervention to Improve Perinatal Continuum of Care in GuatemalaR21HD084114 · NICHD · EMORY UNIVERSITY · PI CLIFFORD, GARI DAVID · 2015 to 2016
$374k
Eunice Kennedy Shriver National Institute of Child Health and Human Development 1R21HD084114-01NICHD NIH HHS R21 HD084114
6 · The paper itself

Abstract

BACKGROUND/

objectiveGuatemala's indigenous Maya population has one of the highest perinatal and maternal mortality rates in Latin America. In this population most births are delivered at home by traditional birth attendants (TBAs), who have limited support and linkages to public hospitals. The goal of this study was to characterize the detection of maternal and perinatal complications and rates of facility-level referral by TBAs, and to evaluate the impact of a mHealth decision support system on these rates.

methodsA pragmatic one-year feasibility trial of an mHealth decisions support system was conducted in rural Maya communities in collaboration with TBAs. TBAs were individually randomized in an unblinded fashion to either early-access or later-access to the mHealth system. TBAs in the early-access arm used the mHealth system throughout the study. TBAs in the later-access arm provided usual care until crossing over uni-directionally to the mHealth system at the study midpoint. The primary study outcome was the monthly rate of referral to facility-level care, adjusted for birth volume.

resultsForty-four TBAs were randomized, 23 to the early-access arm and 21 to the later-access arm. Outcomes were analyzed for 799 pregnancies (early-access 425, later-access 374). Monthly referral rates to facility-level care were significantly higher among the early-access arm (median 33 referrals per 100 births, IQR 22-58) compared to the later-access arm (median 20 per 100, IQR 0-30) (p = 0.03). At the study midpoint, the later-access arm began using the mHealth platform and its referral rates increased (median 34 referrals per 100 births, IQR 5-50) with no significant difference from the early-access arm (p = 0.58). Rates of complications were similar in both arms, except for hypertensive disorders of pregnancy, which were significantly higher among TBAs in the early-access arm (RR 3.3, 95% CI 1.10-9.86).

conclusionsReferral rates were higher when TBAs had access to the mHealth platform. The introduction of mHealth supportive technologies for TBAs is feasible and can improve detection of complications and timely referral to facility-care within challenging healthcare delivery contexts.

trial registrationClinicaltrials.gov NCT02348840 .

Indexed as

Continuity of Patient CareDecision Support TechniquesHome ChildbirthMidwiferyPerinatal CareTelemedicineAdolescentAdultAgedChildFeasibility StudiesFemaleGuatemalaHumansInfant, NewbornMaternal MortalityBarriers to careGuatemalaIndigenousLay midwivesmHealthPerinatal monitoringReferral systemResource-constrained healthcareTraditional birth attendants

Identifiers

PMID29973229
PMCPMC6033207
OpenAlexW2811327863

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.