Evidence map›Paper›PMID 29973221›Full record

ArticlePediatric rheumatology online journal2018

Frequency of CD19

Qianzi Zhao, Lawrence K Jung

Open access · goldAbstract read
In one paragraph

Article in Pediatric rheumatology online journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Innate Lymphocytes in Inflammatory Arthritis.Frontiers in immunology · 2020
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Qianzi ZhaoDivision of Rheumatology, Children's National Medical Center, 111 Michigan Ave, NW, Washington, DC, 20010, USA.
Lawrence K JungDivision of Rheumatology, Children's National Medical Center, 111 Michigan Ave, NW, Washington, DC, 20010, USA. Ljung@childrensnational.org.ORCID http://orcid.org/0000-0001-6366-1736
Children's National · US

Funding

Center for Cancer and Immunology, Children's Research Institute Pilot research grant
6 · The paper itself

Abstract

backgroundTo understand the relationship between regulatory B cells (Bregs) and juvenile idiopathic arthritis (JIA), we analyzed the percentages of Bregs and their function in peripheral blood (PB) and synovial fluid (SF) of JIA patients.

methodsTwenty-one JIA patients and 11 children with growing pain but without known rheumatic diseases as controls were included. The B cell phenotype and intracellular production of IL-10 of Bregs were assessed by flow cytometry. Mononuclear cells from PB and SF were stimulated to produce IL-10 in vitro for the identification of IL-10- producing regulatory B cells.

resultsThe percentage of CD24

conclusionsThe inability of the host to produce enough regulatory B cells in PB and especially in SF of JIA patients may contribute to the disease, especially the local inflammation.

Indexed as

AdolescentADP-ribosyl Cyclase 1Antigens, CD19Arthritis, JuvenileB-Lymphocytes, RegulatoryCD24 AntigenCell Culture TechniquesChildFemaleFlow CytometryHumansInfantInterleukin-10MaleMembrane GlycoproteinsSynovial FluidADP-ribosyl Cyclase 1Antigens, CD19CD19 molecule, humanCD24 AntigenCD24 protein, humanCD38 protein, humanIL10 protein, humanInterleukin-10Membrane GlycoproteinsB lymphocytesCytokinesInflammationJuvenile idiopathic arthritisSynovial fluid

Identifiers

PMID29973221
PMCPMC6033228
OpenAlexW2811489720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.