ArticleBMC veterinary research2018
Effects of low-molecular-weight chitosan on the growth performance, intestinal morphology, barrier function, cytokine expression and antioxidant system of weaned piglets.
Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Effects of black soldier fly replacing fish meal on growth performance, serum parameters, and intestinal microbiota of weaned piglets.Journal of animal science · 2026Article
- Preparation of low molecular weight chitosan through hydroxyl radicals generated via hydrodynamic cavitation.Ultrasonics sonochemistry · 2025Article
- The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.Protoplasma · 2025Article
- Dietary Chitosan Attenuates High-Fat Diet-Induced Oxidative Stress, Apoptosis, and Inflammation in Nile Tilapia (Biology · 2024Article
- Yeast Peptides Improve the Intestinal Barrier Function and Alleviate Weaning Stress by Changing the Intestinal Microflora Structure of Weaned Lambs.Microorganisms · 2023Article
- Transcriptome wide analyses reveal intraspecific diversity in thermal stress responses of a dominant habitat-forming species.Scientific reports · 2023Article
- Chitosan: a promising natural polysaccharide feed additive in poultry production systems.Iranian journal of veterinary research · 2023Review
- Full-fat field cricket (Gryllus bimaculatus) as a substitute for fish meal and soybean meal for weaning piglets: effects on growth performance, intestinal health, and redox status.Journal of animal science · 2022Article
- 4-Phenylbutyric acid accelerates rehabilitation of barrier function in IPEC-J2 cell monolayer model.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- The Protect Effects of Chitosan Oligosaccharides on Intestinal Integrity by Regulating Oxidative Status and Inflammation under Oxidative Stress.Marine drugs · 2021Article
- Low-Molecular-Weight Chitosan Attenuates Lipopolysaccharide-Induced Inflammation in IPEC-J2 Cells by Inhibiting the Nuclear Factor-κB Signalling Pathway.Molecules (Basel, Switzerland) · 2021Article
- Overall assessment of antibiotic substitutes for pigs: a set of meta-analyses.Journal of animal science and biotechnology · 2021Article
- Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications.Molecules (Basel, Switzerland) · 2020Review
- Opportunities of prebiotics for the intestinal health of monogastric animals.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2020Review
- The Effects of the Marine-Derived Polysaccharides Laminarin and Chitosan on Aspects of Colonic Health in Pigs Challenged with Dextran Sodium Sulphate.Marine drugs · 2020Article
- Effects of dietary supplementation of chitosan on immune function in growing Huoyan geese.Poultry science · 2020Article
- Article
- Microbiome Analysis Investigating the Impacts of Fermented Spent Mushroom Substrates on the Composition of Microbiota in Weaned Piglets Hindgut.Frontiers in veterinary science · 2020Article
- Chitosan Oligosaccharides Protect Sprague Dawley Rats from Cyclic Heat Stress by Attenuation of Oxidative and Inflammation Stress.Animals : an open access journal from MDPI · 2019Article
- Amelioration of EnterotoxigenicInternational journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChitosan was used as an alternative to promote the growth of weaned piglets. And low-molecular-weight chitosan (LC) is one of chitosan derivatives and maintain beneficial biological properties of chitoson. The present experiment was carried out to examine the effects of LC on the growth performance, intestinal morphology, barrier function, cytokine expression, and antioxidant system of weaned piglets.
resultsA total of 40 piglets weaned at 21 d of age, with average body weight 6.37 ± 0.08 kg, were randomly assigned (5 pens/diet; 4 pigs/pen) to 2 treatments (a basal diet and the basal diet supplemented with 50 mg/kg LC) and were fed for 28 d. Compared with the control group, average daily feed intake (ADFI), and the expression of intestinal barrier protein ZO-1 was increased (P < 0.05) when the piglets fed the diet supplemented with LC. No significant differences were found in average daily gain (ADG, P > 0.05), gain-to-feed ratio (G:F, P > 0.05), the incidence of diarrhea (P > 0.05), or the antioxidant capacity (P > 0.05) between two groups. The expression of IL-1β and TNF-α in jejunal mucosa were significantly decreased (P < 0.05) in piglets fed the LC-supplemented diet in comparison to the control.
conclusionThe results of this study indicate that dietary supplementation with LC at 50 mg/kg was effective for enhancing the growth performance in weaned piglets, improving intestinal barrier function and alleviating intestinal inflammation.
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