Trial reportThrombosis and haemostasis2018
Fentanyl Delays the Platelet Inhibition Effects of Oral Ticagrelor: Full Report of the PACIFY Randomized Clinical Trial.
Trial report in Thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02683707 (The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Pooled it
- Methoxyflurane Instead of Morphine in Acute Coronary Syndrome Patients: Results of the Randomized Controlled METHANE-SIRIO 4 Study.Thrombosis and haemostasis · 2026Trial
- Comparative effects of fentanyl versus morphine on platelet inhibition induced by ticagrelor in patients with ST-segment elevation myocardial infarction: Full results of the PERSEUS randomized trial.Cardiology journal · 2022Trial
- Determinants of high platelet reactivity in patients with acute coronary syndromes treated with ticagrelor.Scientific reports · 2019Trial
- Sedation Strategy, Procedural Comfort, and Clinically Detected Radial Artery Spasm During Transradial Coronary Angiography: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Changes in platelet maturity and reactivity following acute ST-segment elevation myocardial infarction.Research and practice in thrombosis and haemostasis · 2025Article
- Application of analgesics in emergency services in Germany: a survey of the medical directors.BMC emergency medicine · 2023Article
- Interactions of fentanyl with blood platelets and plasma proteins: platelet sensitivity to prasugrel metabolite is not affected by fentanyl under in vitro conditions.Pharmacological reports : PR · 2023Article
- Analgesic drug use in patients with STEMI: Current perspectives and challenges.Frontiers in medicine · 2023Review
- Pre-hospital treatment of patients with acute coronary syndrome: Recommendations for medical emergency teams. Expert position update 2022.Cardiology journal · 2022Article
- Influence of METHoxyflurane on ANtiplatelet Effect of ticagrelor in patients with unstable angina pectoris: Rationale and a protocol of a randomized clinical METHANE-SIRIO 4 study.Cardiology journal · 2022Article
- P2YFrontiers in cardiovascular medicine · 2022Review
- Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardial infarction: A post-hoc analysis of the AVOID study.International journal of cardiology. Heart & vasculature · 2021Article
- Antithrombotic and anticoagulation therapies in cardiogenic shock: a critical review of the published literature.ESC heart failure · 2021Review
- STEMI care 2021: Addressing the knowledge gaps.American heart journal plus : cardiology research and practice · 2021Review
- Prehospital opioid dose and myocardial injury in patients with ST elevation myocardial infarction.Open heart · 2020Observational
- Opioids during coronary interventions in cath lab - Need reconsideration?Indian journal of anaesthesia · 2020Article
- Pharmacokinetics and Pharmacodynamics of Approved and Investigational P2Y12 Receptor Antagonists.Clinical pharmacokinetics · 2020Review
Corrections and comments
- Commented on by
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Morphine delays oral P2Y CLINICAL
trial registrationhttps://clinicaltrials.gov/ct2/show/NCT02683707 (: NCT02683707).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.