Evidence map›Paper›PMID 29972658›Full record

Observational studyThe Journal of asthma : official journal of the Association for the Care of Asthma2019

Respiratory waveform variation can prevent pulsus paradoxus measurement by sphygmomanometry.

Jonas Alexander Pologe, Kara Lynn Wolley, Donald H Arnold

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The Journal of asthma : official journal of the Association for the Care of Asthma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Prediction of acute asthma exacerbation severity and interrater reliability of manual pulsus paradoxus measurement.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jonas Alexander Pologea Department of Electrical Engineering , Kestrel Labs, Inc. , Boulder , CO , USA.
Kara Lynn Wolleyb Department of Integrative Physiology , Kestrel Labs, Inc. , Boulder , CO , USA.
Donald H Arnoldc Divison of Emergency Medicine, Vanderbilt University School of Medicine, Vanderbilt Children's Hospital , Nashville , TN , USA.
Kestrel Labs (United States) · USVanderbilt University · US

Funding

Pulse Oximeter Innovation to Measure Pulsus Paradoxus and Respiratory Disease SeverityR43HL131165 · NHLBI · KESTREL LABS, INC. · PI ARNOLD, DONALD HAYES, POLOGE, JONAS ALEXANDER · 2016 to 2016
$150k
NHLBI NIH HHS R43 HL131165
6 · The paper itself

Abstract

backgroundPulsus paradoxus (PP) represents increased fluctuation of systolic pressure during the respiratory cycle. PP increases in pathologic conditions, including asthma and other obstructive airways diseases. Respiratory waveform variation (RWV) represents arterial-waveform baseline variability resulting from intra-pleural pressure changes during the respiratory cycle in the presence of airway obstruction. It is not known whether RWV influences manual PP measurement using a sphygmomanometer and stethoscope.

methodsWe performed an observational study in six healthy adults. Participants performed tidal-breathing through a breathing apparatus with pre-determined inspiratory (0-45.6 cm H

resultsIn this study, PP values measured without applied airway resistance exceeded 10 mmHg, the traditional definition of PP, in five of the six participants. Manual measurement of PP would not be possible at greater RWV because the maximum diastolic pressure exceeded minimum systolic pressure during RWV.

conclusionsPP in normal adults may exceed 10 mmHg, and RWV may be of sufficient magnitude to preclude manual PP measurement.

Indexed as

Blood PressureRespirationAdultAsthmaHumansMaleSphygmomanometersYoung Adultblood pressure.Pathophysiologyphysiological disorderspulsus paradoxus

Identifiers

PMID29972658
PMCPMC6395523
OpenAlexW2810663859

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.