Evidence map›Paper›PMID 29971969›Full record

Trial reportESC heart failure2018

Low frequency electrical muscle stimulation and endothelial function in advanced heart failure patients.

Stuart Ennis, Gordon McGregor, Robert Shave, Barry McDonnell, Andrew Thompson, Prithwish Banerjee, Helen Jones

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Cachexia as a common characteristic in multiple chronic disease.Journal of cachexia, sarcopenia and muscle · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Stuart EnnisUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Gordon McGregorUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Robert ShaveCardiff Metropolitan University, Cardiff, UK.
Barry McDonnellCardiff Metropolitan University, Cardiff, UK.
Andrew ThompsonUniversity of Liverpool, Liverpool, UK.
Prithwish BanerjeeUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Helen JonesLiverpool John Moores University, Liverpool, UK.
Cardiff Metropolitan University · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBCoventry University · GBLiverpool John Moores University · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimObtain initial estimates of the change in brachial artery endothelial function and maximal oxygen uptake (VO METHODS AND

resultsUsing a double blind, randomized design, 35 patients with chronic heart failure (New York Heart Association class III-IV) were assigned to 8 weeks (5 × 60 min per week) of either LF-EMS (4 Hz, continuous) or sham (skin level stimulation only) of the quadriceps and hamstrings muscles. Four of the five sessions were at home and one under supervision. Ultrasound images of resting brachial artery diameter and post 5 min occlusion to determine flow-mediated dilation (FMD), a marker of vascular function and peak oxygen uptake (VO

conclusionsImprovements in FMD with LF-EMS may have a clinically meaningful effect as higher FMD is associated with better prognosis. This is a preliminary finding, and a larger trial is warranted.

Indexed as

AgedBrachial ArteryDouble-Blind MethodElectric Stimulation TherapyEndothelium, VascularFeasibility StudiesFemaleHeart FailureHumansMaleQuadriceps MuscleStroke VolumeTreatment OutcomeUltrasonographyVasodilationAdvanced heart failureCardiac rehabilitationEndothelial function electrical muscle stimulationFlow-mediated dilationNeuromuscular electrical stimulation

Identifiers

PMID29971969
PMCPMC6073028
OpenAlexW2893961535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.