Evidence map›Paper›PMID 29971868›Full record

Trial reportAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2018

The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging.

Joseph Allencherril, Yama Fakhri, Henrik Engblom, Einar Heiberg, Marcus Carlsson, Jean-Luc Dubois-Rande, Sigrun Halvorsen, Trygve S Hall, Alf-Inge Larsen, Svend Eggert Jensen and 5 more

Open access · greenAbstract readClinical Trial, Phase IIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018
    Trial
  2. Review
  3. Article
  4. Diagnostic flowchart to estimate the morphology of left descending artery lesions by initial electrocardiogram in ST-elevation myocardial infarction.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020
    Article
  5. The established electrocardiographic classification of anterior wall myocardial infarction misguides clinicians in terms of infarct location, extent and prognosis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
  6. Reply.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
  7. Deblurring the significance of ST-elevation in aVL in anterolateral myocardial infarction.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 6 countries.

Joseph AllencherrilSection of Cardiology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0003-4940-0374
Yama FakhriDepartment of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Henrik EngblomDepartment of Clinical Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Einar HeibergDepartment of Clinical Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Marcus CarlssonDepartment of Clinical Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Jean-Luc Dubois-RandeAssistance Publique Hôpitaux de Paris, Hôpital Henri Mondor, Créteil, France.
Sigrun HalvorsenDepartment of Cardiology B, Faculty of Medicine, Oslo University Hospital Ullevål, University of Oslo, Oslo, Norway.
Trygve S HallDepartment of Cardiology B, Faculty of Medicine, Oslo University Hospital Ullevål, University of Oslo, Oslo, Norway.
Alf-Inge LarsenDepartment of Cardiology, Stavanger University Hospital, Stavanger, Norway.
Svend Eggert JensenDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Hakan ArhedenDepartment of Clinical Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Dan AtarDepartment of Cardiology B, Faculty of Medicine, Oslo University Hospital Ullevål, University of Oslo, Oslo, Norway.
Peter ClemmensenDepartment of Medicine, Nykøbing F Hospital, Nykøbing F, Denmark.
Maria Sejersten RipaDepartment of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Yochai BirnbaumSection of Cardiology, Baylor College of Medicine, Houston, Texas.
Lund University · SEOslo University Hospital · NOBaylor College of Medicine · USUniversity of Copenhagen · DKAalborg University Hospital · DKAssistance Publique – Hôpitaux de Paris · FRStavanger University Hospital · NOUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterolateral myocardial infarction (MI) is traditionally defined on the electrocardiogram by ST-elevation (STE) in I, aVL, and the precordial leads. Traditional literature holds STE in lead aVL to be associated with occlusion proximal to the first diagonal branch of the left anterior descending coronary artery. However, concomitant ischemia of the inferior myocardium may theoretically lead to attenuation of STE in aVL. We compared segmental distribution of myocardial area at risk (MaR) in patients with and without STE in aVL.

methodsWe identified patients in the MITOCARE study presenting with a first acute MI and new STE in two contiguous anterior leads from V

resultsA total of 32 patients met inclusion criteria; 13 patients with and 19 without STE in lead aVL. MaR > 20% at the basal anterior segment was seen in 54% of patients with aVL STE, and 11% of those without (p = 0.011). MaR > 20% at the apical inferior segment was seen in 62% and 95% of patients with and without aVL STE, respectively (p = 0.029). The total MaR was not different between groups (44% ± 10% and 39% ± 8.3% respectively, p = 0.15).

conclusionPatients with anterior STEMI and concomitant STE in aVL have less MaR in the apical inferior segment and more MaR in the basal anterior segment.

Indexed as

GadoliniumRadiographic Image EnhancementAgedAnterior Wall Myocardial InfarctionCoronary StenosisDenmarkDouble-Blind MethodElectrocardiographyFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedPrognosisSensitivity and SpecificitySeverity of Illness IndexGadolinium

Identifiers

PMID29971868
PMCPMC6931512
OpenAlexW2811303921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.