Evidence map›Paper›PMID 29971782›Full record

ArticleInternational journal of cancer2018

Long isoform of VEGF stimulates cell migration of breast cancer by filopodia formation via NRP1/ARHGAP17/Cdc42 regulatory network.

Marina Kiso, Sunao Tanaka, Shigehira Saji, Masakazu Toi, Fumiaki Sato

Open access · hybridAbstract read
In one paragraph

Article in International journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  8. Neuropilin (NRPs) Related Pathological Conditions and Their Modulators.International journal of molecular sciences · 2022
    Review
  9. Fixing the GAP: The role of RhoGAPs in cancer.European journal of cell biology · 2022
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marina KisoDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sunao TanakaDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shigehira SajiDepartment of Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Masakazu ToiDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Fumiaki SatoDepartment of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0001-8186-9290
Kyoto University · JPFukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VEGF stimulates endothelial cells as a key molecule in angiogenesis. VEGF also works as a multifunction molecule, which targets a variety of cell members in the tumor microenvironment. We aimed to reveal VEGF-related molecular mechanisms on breast cancer cells. VEGF-knocked-out MDA-MB-231 cells (231

Indexed as

Breast NeoplasmsCell Line, TumorCell MovementEndothelial CellsFemaleGTPase-Activating ProteinsHumansNeovascularization, PathologicNeuropilin-1Protein BindingProtein IsoformsPseudopodiaReceptors, Vascular Endothelial Growth FactorSignal TransductionVascular Endothelial Growth Factor AARHGAP17 protein, humanGTPase-Activating ProteinsNeuropilin-1NRP1 protein, humanProtein IsoformsReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVEGFA protein, humanARHGAP17breast cancercdc42filopodiaisoformmigrationneuropilinVEGF

Identifiers

PMID29971782
PMCPMC6282968
OpenAlexW2810035719

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.