SynthesisAIDS and behavior2019
Comparison of Antiretroviral Therapy Adherence Among HIV-Infected Older Adults with Younger Adults in Africa: Systematic Review and Meta-analysis.
Synthesis in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05010317 (Acceptability, Feasibility and Effectiveness of a Mindfulness Based Intervention to Promote Adherence to Antiretroviral Therapy Among Adolescents in Kampala.), which is not on this map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Acceptability, Feasibility and Effectiveness of a Mindfulness Based Intervention to Promote Adherence to Antiretroviral Therapy Among Adolescents in Kampala.
Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Depression management and antiretroviral treatment outcome among people living with HIV in Northwest and East regions of Cameroon.BMC infectious diseases · 2022Trial
- The Effect of a Group-Based Mindfulness and Acceptance Training on Psychological Flexibility and Adherence to Antiretroviral Therapy Among Adolescents in Uganda: An Open-Label Randomized Trial.Journal of the International Association of Providers of AIDS CareTrial
- Demographic and Socioeconomic Factors Associated With ART Nonadherence Among 15 Years and Older South Africans. Evidence From the 2022 Cross-Sectional Population-Based Household Survey.AIDS research and treatment · 2026Article
- Prevalence and incidence of non-communicable diseases among older adults living with HIV on antiretroviral therapy in Northern Haiti: A retrospective cohort study.PLOS global public health · 2026Article
- Educational attainment and chronic HIV treatment adherence in southern and eastern Africa.PloS one · 2026Article
- Disparities in antiretroviral therapy adherence among selected adult subpopulations with HIV/AIDS in Tanzania: Analysis of a population-based survey, 2022/23.PLOS global public health · 2025Article
- Antiretroviral Treatment Adherence among People Living with HIV in Taipei, Taiwan.Journal of epidemiology and global health · 2024Article
- Association of coping mechanisms with medication adherence among young People living with HIV (PLHIV) in Klang Valley.Heliyon · 2024Article
- Effects of the COVID-19 pandemic on HIV service delivery and viral suppression: Findings from the SHARP program in Northern Nigeria.PloS one · 2024Article
- Factors associated with HIV viremia in transgender women and transvestites in five Brazilian capitals, 2019-2021: a multicenter study.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2024Article
- Acceptability of an adapted mindfulness and acceptance-based intervention to support adolescents with HIV: A qualitative study with Ugandan health care providers.Journal of contextual behavioral science · 2023Article
- Identifying the needs of older people living with HIV (≥ 50 years old) from multiple centres over the world: a descriptive analysis.AIDS research and therapy · 2023Article
- Culturally adapting a mindfulness and acceptance-based intervention to support the mental health of adolescents on antiretroviral therapy in Uganda.PLOS global public health · 2023Article
- Late-onset opportunistic infections while receiving anti-retroviral therapy in Latin America: burden and risk factors.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Adherence to HIV Antiretroviral Therapy Among Pregnant and Breastfeeding Women, Non-Pregnant Women, and Men in Burkina Faso: Nationwide Analysis 2019-2020.Patient preference and adherence · 2022Article
- "Deadly", "fierce", "shameful": notions of antiretroviral therapy, stigma and masculinities intersecting men's life-course in Blantyre, Malawi.BMC public health · 2021Article
- Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop.AIDS research and human retroviruses · 2021Article
- Body image and antiretroviral therapy adherence among people living with HIV: a protocol for a systematic review and meta-analysis.BMJ open · 2021Article
- 'Too old to test?': A life course approach to HIV-related risk and self-testing among midlife-older adults in Malawi.BMC public health · 2021Article
- A Multi-Dimensional Characterization of Aging and Wellbeing Among HIV-Positive Adults in Malawi.AIDS and behavior · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As access to antiretroviral treatment in low- and middle-income countries improves, the number of older adults (aged ≥ 50 years) living with HIV is increasing. This study compares the adherence to antiretroviral treatment among older adults to that of younger adults living in Africa. We searched PubMed, Medline, Cochrane CENTRAL, CINAHL, Google Scholar and EMBASE for keywords (HIV, ART, compliance, adherence, age, Africa) on publications from 1st Jan 2000 to 1st March 2016. Eligible studies were pooled for meta-analysis using a random-effects model, with the odds ratio as the primary outcome. Twenty studies were included, among them were five randomised trials and five cohort studies. Overall, we pooled data for 148,819 individuals in two groups (older and younger adults) and found no significant difference in adherence between them [odds ratio (OR) 1.01; 95% CI 0.94-1.09]. Subgroup analyses of studies using medication possession ratio and clinician counts to measure adherence revealed higher proportions of older adults were adherent to medication regimens compared with younger adults (OR 1.06; 95% CI 1.02-1.11). Antiretroviral treatment adherence levels among older and younger adults in Africa are comparable. Further research is required to identify specific barriers to adherence in the aging HIV affected population in Africa which will help in development of interventions to improve their clinical outcomes and quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.