Evidence map›Paper›PMID 29971629›Full record

ArticleMikrochimica acta2018

Synthesis of Au@Ag core-shell nanostructures with a poly(3,4-dihydroxy-L-phenylalanine) interlayer for surface-enhanced Raman scattering imaging of epithelial cells.

Haibin Wen, Peichun Jiang, Yuling Hu, Gongke Li

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Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haibin WenSchool of Chemistry, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
Peichun JiangSchool of Chemistry, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
Yuling HuSchool of Chemistry, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. ceshyl@mail.sysu.edu.cn.
Gongke LiSchool of Chemistry, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. cesgkl@mail.sysu.edu.cn.ORCID 0000-0003-3750-6358

Funding

the Guangdong Provincial Natural Science Foundation of China 2015A030311020the Guangdong Provincial Natural Science Foundation of China 2017A030313070the Guangzhou Science and Technology Program of China 201604020165the Guangzhou Science and Technology Program of China 201704020040the National Natural Science Foundation of China 21475153 and 21675178the National Natural Science Foundation of China 21575168the Special Funds for Public Welfare Research and Capacity Building in Guangdong Province of China 2015A030401036
6 · The paper itself

Abstract

Poly(3,4-dihydroxy-L-phenylalanine) (polyDOPA) is a stable and biocompatible reducing agent. A versatile strategy is described here for the synthesis of core-shell Au@Ag nanostructures containing a polyDOPA interlayer. The latter provides abundant sites for deposition of nanocomposites, to immobilize molecules and to grow shells. The Au@polyDOPA@Ag nanoparticles are shown to generate strong and stable surface-enhanced Raman spectroscopy (SERS) signals compared to bare AuNPs and bare AgNPs. Folic acid was then immobilized on Au@polyDOPA@Ag nanoparticles and then applied to SERS imaging of human lung adenocarcinoma cell line A549 by the specific recognition of the folic acid receptor. The folic acid-conjugated SERS tags were promising to be nanoplatforms for imaging of cancer cells. Graphical abstract An Au@Ag core-shell nanostructures SERS nanotag with a polyDOPA interlayer was fabricated and then applied to SERS imaging of epithelial cells. (DOPA: 3,4-Dihydroxy-[

Indexed as

A549 CellsChemistry Techniques, SyntheticDihydroxyphenylalanineEpithelial CellsGoldHumansMetal NanoparticlesMolecular ImagingNanotechnologyPolymersSilverSpectrum Analysis, RamanSurface PropertiesDihydroxyphenylalanineGoldpoly(3,4-dihydroxyphenylalanine)PolymersSilverAu/Ag core-shell nanostructuresCancer cellsEpithelial cellsFolic acidIn situ reductionPolyDOPAPolyDOPA interlayerSERS imagingSERS tagsSurface-enhanced Raman scattering

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What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.