ReviewTranslational gastroenterology and hepatology2018
Vitamin D: a brief overview of its importance and role in inflammatory bowel disease.
Review in Translational gastroenterology and hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship?Reviews in endocrine & metabolic disorders · 2023Review
- Hypocholesterolemia and Inflammatory Biomarkers Act as Predictors of Severe Vitamin D Deficiency in Patients With Crohn's Disease: A Clinical Analysis of 862 Patients in China.Frontiers in nutrition · 2022Article
- Review
- Article
- Managing vitamin D deficiency in inflammatory bowel disease.Frontline gastroenterology · 2019Review
- Higher Sun Exposure is Associated With Lower Risk of Pediatric Inflammatory Bowel Disease: A Matched Case-control Study.Journal of pediatric gastroenterology and nutrition · 2019Article
- The Role of Vitamin D in Elderly Inflammatory Bowel Disease Patients.Gastroenterology & hepatology · 2019Article
- The Role of Vitamin D in Inflammatory Bowel Disease - Assessing Therapeutic and Preventive Potential of Supplementation and Food Fortification.Food technology and biotechnology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D has traditionally been known for its regulation of bone metabolism and homeostasis, but emerging evidence suggests that it also has a broad function in immune regulation, and inflammatory bowel disease (IBD). The etiology of IBD is thought to be multifactorial but stems in part due to the deregulation of the immune response to environmental factors in the setting of a pre-existing genetic disposition. Vitamin D, based on its mechanistic role at the cellular level in T-cell trafficking, had been postulated to have a direct effect on the immune system, This alludes to the fact that vitamin D may have the ability to not only potentiate the IBD phenotype, but also in doing so, its supplementation may serve a therapeutic role in amelioration of the diseased state. We review in this article the current literature as it pertains to the basic mechanism of Vitamin D, its role in the pathogenicity of IBD, how it regulates our immune system, interpretation and accuracy of obtaining levels, and the role there may be in supplementation in IBD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.