ReviewFrontiers in cardiovascular medicine2018
Transcatheter Aortic Valve Replacement and Concomitant Mitral Regurgitation.
Review in Frontiers in cardiovascular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Transapical Mitral TEER and Aortic Regurgitation TAVR With Dedicated Device in a Patient With Extreme Scoliosis.JACC. Case reports · 2026Article
- The evolution of concomitant mitral regurgitation in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement: a prospective multi-center China-DVD2 cohort study.Cardiology journal · 2026Article
- Increase in Aortic Valve Mean Gradients One Day After Transcatheter Aortic Valve Implantation: The Role of Mitral Regurgitation.Cardiology research · 2025Article
- Severe Aortic Stenosis Associated with Other Valve Diseases: Open Surgery or Percutaneous Treatment?Reviews in cardiovascular medicine · 2024Review
- Transcatheter mitral valve implantation using the Tendyne valve in a patient with prior transcatheter aortic valve implantation: a case report.European heart journal. Case reports · 2023Article
- Update on Percutaneous Treatment for HFrEF: A Great Armamentarium for a Poor Ventricular Function.Reviews in cardiovascular medicine · 2023Review
- Prognostic relevance of mitral and tricuspid regurgitation after transcatheter aortic valve implantation: Impact of follow-up time point for decision-making.Frontiers in cardiovascular medicine · 2023Article
- Concomitant mitral regurgitation in patients with low-gradient aortic stenosis: an analysis from the German Aortic Valve Registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.Journal of clinical medicine · 2021Article
- Mitral annular disjunction in patients with severe aortic stenosis: Extent and reproducibility of measurements with computed tomography.European journal of radiology open · 2021Article
- Mitral regurgitation after transcatheter aortic valve replacement.Journal of thoracic disease · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitral regurgitation frequently coexists in patients with severe aortic stenosis. Patients with moderate to severe mitral regurgitation at the time of transcatheter aortic valve replacement are at increased risk of future adverse events. Whether concomitant mitral regurgitation is independently associated with worse outcomes after TAVR remains a matter of debate. The optimal therapeutic strategy in these patients-TAVR with evidence-based heart failure therapy, combined TAVR and transcatheter mitral valve intervention, or staged transcatheter therapies-is ill-defined, and guideline-based recommendations in patients at increased risk for open heart surgery are lacking. Hence, a thorough evaluation of the aortic and mitral valve anatomy and function, along with an in-depth assessment of the patients' baseline risk profile, provides the basis for an individualized treatment approach. The aim of this review is therefore to give an overview of the current literature on mitral regurgitation in TAVR, focusing on different diagnostic and therapeutic strategies and optimal clinical decision making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.