Evidence map›Paper›PMID 29971210›Full record

ArticleKidney research and clinical practice2018

Obesity may be erythropoietin dose-saving in hemodialysis patients.

Ghada M El-Kannishy, Abir F Megahed, Mona M Tawfik, Ghada El-Said, Rabab T Zakaria, Nahed A Mohamed, Eman M Taha, Alzhraa A Ammar, Abeer M Abd Eltawab, Nagy A Sayed-Ahmed

Open access · diamondAbstract read
In one paragraph

Article in Kidney research and clinical practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Ghada M El-KannishyMansoura Nephrology and Dialysis Unit (MNDU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Abir F MegahedNephrology Unit, Mansoura Military Hospital, Mansoura, Egypt.
Mona M TawfikMansoura Nephrology and Dialysis Unit (MNDU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ghada El-SaidMansoura Nephrology and Dialysis Unit (MNDU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Rabab T ZakariaEl Minia Hemodialysis Center, El Minia, Egypt.
Nahed A MohamedDialysis Unit, Abokeir Hospital, Alexandria, Egypt.
Eman M TahaTemy Alamdeed Dialysis Center, Dakahlyia, Egypt.
Alzhraa A AmmarDialysis Unit, Alexandria Fever Hospital, Alexandria, Egypt.
Abeer M Abd EltawabDialysis Unit, Raas El Teen Hospital, Alexandria, Egypt.
Nagy A Sayed-AhmedMansoura Nephrology and Dialysis Unit (MNDU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Mansoura University · EGAlexandria University · EGAlyn Hospital · ILDiversité, adaptation et développement des plantes · FRInova Alexandria Hospital · USMansoura University Hospital · EGMinia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn dialysis patients, the obesity-survival paradox still requires an explanation. Anemia and high doses of erythropoiesis-stimulating agents (ESAs) are associated with worse outcomes in the hemodialysis (HD) population. In the present study, we explored the relation between obesity and anemia control in a sample of maintenance HD patients in Egypt.

methodsThis multicenter observational study included 733 patients on maintenance HD from 9 hemodialysis centers in Egypt. Clinical and laboratory data as well as average doses of ESAs and parenteral iron were recorded. The erythropoietin resistance index (ERI) was calculated.

resultsObesity, defined as a body mass index (BMI) ≥ 30 kg/m

conclusionOur study adds more evidence to obesity-associated advantages in HD patients. BMI may determine ESA response, with better responses observed in patients with higher BMIs.

Indexed as

Body mass indexErythropoiesis-stimulating agentsObesityRenal Dialysis

Identifiers

PMID29971210
PMCPMC6027808
OpenAlexW2811052285

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.