Observational studyBehavioural neurology2018
Risk Factors for the Progression of Mild Cognitive Impairment in Different Types of Neurodegenerative Disorders.
Observational study in Behavioural neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Effectiveness of the Hayling and Brixton Tests for Detecting Dementia, Progressive Cognitive Decline, and Mild Cognitive Impairment in Middle to Older Aged Adults: A Systematic Review and Meta-analysis.Neuropsychology review · 2026Pooled it
- Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis.Nutrients · 2023Pooled it
- Effects of Tai Chi on Patients with Mild Cognitive Impairment: A Systematic Review and Meta-analysis of Randomized Controlled Trials.BioMed research international · 2021Pooled it
- Integrative genome-scale metabolic model of GABAergic neurons reveals metabolic signatures across the mild cognitive impairment - Alzheimer disease continuum.Frontiers in systems biology · 2026Article
- Exploring the pathogenic mechanisms of dementia risk factors: a task-fMRI study of mild cognitive impairment.Frontiers in neuroscience · 2026Article
- Effects of two different doses of HIFT on physical function, cognitive performance, and quality of life in older adults with mild cognitive impairment: A randomized controlled trial.Journal of exercise science and fitness · 2025Article
- Risk of impairment in cognitive instrumental activities of daily living for sexual and gender minority adults with reported Parkinson's disease.The Clinical neuropsychologist · 2025Article
- Brain-Gut Interplay: Cognitive Performance and Biomarker Correlations in IBD Patients.Journal of clinical medicine · 2025Article
- Formulating Treatment to Cure Alzheimer's Dementia: Approach #2.International journal of molecular sciences · 2024Review
- Cognitive Dysfunction and Affective Mood Disorder Screening in Patients With Chronic Inflammatory Bowel Disease: Protocol for a Prospective Case-Control Study.JMIR research protocols · 2023Article
- Somatic comorbidity and the progression of cognitive impairment.Frontiers in aging neuroscience · 2023Article
- Persistent neurobehavioral and neurochemical anomalies in middle-aged rats after maternal diazinon exposure.Toxicology · 2022Article
- Analysis of neuropathological comorbid conditions in elderly patients with mild cognitive impairment in a tertiary care center in South India.Journal of family medicine and primary care · 2022Article
- The Influence of Serum Uric Acid on the Brain and Cognitive Dysfunction.Frontiers in psychiatry · 2022Review
- Rate of conversion from mild cognitive impairment to dementia in a Thai hospital-based population: A retrospective cohort.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Segmental Bioimpedance Variables in Association With Mild Cognitive Impairment.Frontiers in nutrition · 2022Article
- Galectin-3 Involvement in Cognitive Processes for New Therapeutic Considerations.Frontiers in cellular neuroscience · 2022Review
- MRI quantitative susceptibility mapping of the substantia nigra as an early biomarker for Lewy body disease.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021Article
- Motoric Cognitive Risk Syndrome in Polypharmacy.Journal of the American Geriatrics Society · 2020Article
- A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice.Pharmaceutics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMild cognitive impairment (MCI) is a transitional state between normal aging and early dementia. It has a heterogeneous etiology and clinical course. This study aimed to examine the factors associated with the progression of MCI in different types of dementia disorders.
methodA retrospective, longitudinal, observational study of outpatients with MCI was conducted at a medical center in northern Taiwan. Patient medical records were reviewed, and risk factors were analyzed by multivariate analysis.
resultsAmong 279 patients with MCI, 163 (58.4%), 68 (24.4%), and 48 (17.2%) were diagnosed with Alzheimer's disease, vascular cognitive impairment, and Lewy body diseases, respectively. During the observation period, 37.2% of patients progressed to dementia. Older age and a higher Clinical Dementia Rating Scale-Sum of Boxes were associated with the risk of progression. Hyperlipidemia was associated with a decreased risk. Converters were more likely to receive an antidementia prescription.
conclusionOur study suggests the importance of comprehensive clinical profiling, risk factor assessment, and detailed drug history evaluations in improving our understanding and management of dementia subtypes.
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