ArticleFrontiers in plant science2018
The CYP71AZ P450 Subfamily: A Driving Factor for the Diversification of Coumarin Biosynthesis in Apiaceous Plants.
Article in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 37 citations in OpenAlex.
- Elucidating the Furanocoumarin Biosynthetic Pathway inPlants (Basel, Switzerland) · 2026Article
- Chromosome-level genome and population resequencing reveal genetic diversity, demographic history, and climate risk in the East Asian relict treePlant diversity · 2026Article
- Integrated Metabolome and Transcriptome Analysis in Ammi majus L. Revealed Candidate Genes of Furanocoumarins Pathway.Biochemical genetics · 2026Article
- A chromosome-level genome assembly for Ficus carica provides genetic insights into flowerless fig fruit development, psoralen biosynthesis, and drought tolerance.Plant communications · 2025Article
- Integrative multi-omics data provide insights into the biosynthesis of furanocoumarins and mechanisms regulating their accumulation in Angelica dahurica.Communications biology · 2025Article
- The chromosome-scale assembly of theActa pharmaceutica Sinica. B · 2024Article
- Two types of coumarins-specific enzymes complete the last missing steps in pyran- and furanocoumarins biosynthesis.Acta pharmaceutica Sinica. B · 2024Article
- Exceptional evolutionary lability of flower-like inflorescences (pseudanthia) in Apiaceae subfamily Apioideae.American journal of botany · 2022Article
- Root-Secreted Coumarins and the Microbiota Interact to Improve Iron Nutrition in Arabidopsis.Cell host & microbe · 2020Article
- A GDSL lipase-like from Ipomoea batatas catalyzes efficient production of 3,5-diCQA when expressed in Pichia pastoris.Communications biology · 2020Article
- Convergent evolution of the UbiA prenyltransferase family underlies the independent acquisition of furanocoumarins in plants.The New phytologist · 2020Article
- Untargeted Metabolomics Approach Reveals Diverse Responses ofMetabolites · 2019Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The production of coumarins and furanocoumarins (FCs) in higher plants is widely considered a model illustration of the adaptation of plants to their environment. In this report, we show that the multiplication of cytochrome P450 variants within the CYP71AZ subfamily has contributed to the diversification of these molecules. Multiple copies of genes encoding this enzyme family are found in Apiaceae, and their phylogenetic analysis suggests that they have different functions within these plants. CYP71AZ1 from
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