ArticleFrontiers in physiology2018
Validation of Patient-Specific Cerebral Blood Flow Simulation Using Transcranial Doppler Measurements.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Three-dimensional, patient-specific simulation of cerebral blood flow velocities as a new approach for individualized stroke prevention and treatment.Computational and structural biotechnology journal · 2025Article
- Uncertainty quantification of the lattice Boltzmann method focussing on studies of human-scale vascular blood flow.Scientific reports · 2024Article
- Uncertainty quantification of the impact of peripheral arterial disease on abdominal aortic aneurysms in blood flow simulations.Journal of the Royal Society, Interface · 2024Article
- Comparison of computational fluid dynamics with transcranial Doppler ultrasound in response to physiological stimuli.Biomechanics and modeling in mechanobiology · 2024Article
- High resolution simulation of basilar artery infarct and flow within the circle of Willis.Scientific reports · 2023Article
- Parametric analysis of an efficient boundary condition to control outlet flow rates in large arterial networks.Scientific reports · 2022Article
- Validation of a cerebral hemodynamic model with personalized calibration in patients with aneurysmal subarachnoid hemorrhage.Frontiers in bioengineering and biotechnology · 2022Article
- An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method.Scientific reports · 2021Article
- High fidelity blood flow in a patient-specific arteriovenous fistula.Scientific reports · 2021Article
- Uncertainty quantification in classical molecular dynamics.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021Article
- Towards blood flow in the virtual human: efficient self-coupling of HemeLB.Interface focus · 2021Article
- Study protocol of validating a numerical model to assess the blood flow in the circle of Willis.BMJ open · 2020Article
- Lattice-Boltzmann interactive blood flow simulation pipeline.International journal of computer assisted radiology and surgery · 2020Article
- Evaluation of cerebral hemodynamic assessment from time-of-flight magnetic resonance angiography using a topological network-based model with Transcranial Doppler measurements.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
Abstract
We present a validation study comparing results from a patient-specific lattice-Boltzmann simulation to transcranial Doppler (TCD) velocity measurements in four different planes of the middle cerebral artery (MCA). As part of the study, we compared simulations using a Newtonian and a Carreau-Yasuda rheology model. We also investigated the viability of using downscaled velocities to reduce the required resolution. Simulations with unscaled velocities predict the maximum flow velocity with an error of less than 9%, independent of the rheology model chosen. The accuracy of the simulation predictions worsens considerably when simulations are run at reduced velocity, as is for example the case when inflow velocities from healthy individuals are used on a vascular model of a stroke patient. Our results demonstrate the importance of using directly measured and patient-specific inflow velocities when simulating blood flow in MCAs. We conclude that localized TCD measurements together with predictive simulations can be used to obtain flow estimates with high fidelity over a larger region, and reduce the need for more invasive flow measurement procedures.
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