Evidence map›Paper›PMID 29970869›Full record

ArticleNutrients2018

Protective Effect of Pure Sour Cherry Anthocyanin Extract on Cytokine-Induced Inflammatory Caco-2 Monolayers.

Thi Le Phuong Nguyen, Ferenc Fenyvesi, Judit Remenyik, Judit Rita Homoki, Péter Gogolák, Ildikó Bácskay, Pálma Fehér, Zoltán Ujhelyi, Gábor Vasvári, Miklós Vecsernyés and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Thi Le Phuong NguyenDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. nguyen.thi.le.phuong@pharm.unideb.hu.
Ferenc FenyvesiDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. fenyvesi.ferenc@pharm.unideb.hu.
Judit RemenyikDepartment of Feed- and Food Biotechnology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 4030 Debrecen, Hungary. remenyik@agr.unideb.hu.
Judit Rita HomokiDepartment of Feed- and Food Biotechnology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 4030 Debrecen, Hungary. homoki.judit@agr.unideb.hu.
Péter GogolákDepartment of Immunology, Faculty of Medicine, University of Debrecen, 4030 Debrecen, Hungary. gogy@med.unideb.hu.
Ildikó BácskayDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. bacskay.ildiko@pharm.unideb.hu.
Pálma FehérDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. feher.palma@pharm.unideb.hu.
Zoltán UjhelyiDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. ujhelyi.zoltan@pharm.unideb.hu.
Gábor VasváriDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. vasvari.gabor@pharm.unideb.hu.
Miklós VecsernyésDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. vecsernyes.miklos@pharm.unideb.hu.
Judit VáradiDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 4030 Debrecen, Hungary. varadi.judit@pharm.unideb.hu.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthocyanins have several beneficial effects, especially on inflammatory and oxidative conditions. The pro-inflammatory cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), induce damage in the intestinal barrier and participate in the pathogenesis of chronic bowel diseases. A number of fruits have high anthocyanin contents with strong biological activity which can support protective actions. Sour cherry (

Indexed as

Prunus aviumActive Transport, Cell NucleusAnthocyaninsAnti-Inflammatory AgentsCaco-2 CellsColonDose-Response Relationship, DrugElectric ImpedanceFruitGlutathione PeroxidaseHumansInflammatory Bowel DiseasesInterleukin-1betaInterleukin-6Interleukin-8PermeabilityAnthocyaninsAnti-Inflammatory AgentsCXCL8 protein, humanGlutathione PeroxidaseIL6 protein, humanInterleukin-1betaInterleukin-6Interleukin-8Plant ExtractsRELA protein, humanTranscription Factor RelATumor Necrosis Factor-alphaanthocyaninCaco-2inflammationNF-κBpermeabilitysour cherry

Identifiers

PMID29970869
PMCPMC6073755
OpenAlexW2810805659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.