Evidence map›Paper›PMID 29970827›Full record

ReviewInternational journal of molecular sciences2018

Recent Insights on Alzheimer's Disease Originating from Yeast Models.

David Seynnaeve, Mara Del Vecchio, Gernot Fruhmann, Joke Verelst, Melody Cools, Jimmy Beckers, Daniel P Mulvihill, Joris Winderickx, Vanessa Franssens

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Yeast as a Model for Human Disease.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. International journal of molecular sciences · 2023
    Review
  8. Review
  9. Review
  10. Alzheimer's Disease: Significant Benefit from the Yeast-Based Models.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Review
  13. A Toxic Synergy between Aluminium and Amyloid Beta in Yeast.International journal of molecular sciences · 2021
    Article
  14. Article
  15. The Dose-Dependent Pleiotropic Effects of the UBBFrontiers in molecular biosciences · 2021
    Review
  16. Article
  17. Review
  18. Screening and Identification of Potential Peripheral Blood Biomarkers for Alzheimer's Disease Based on Bioinformatics Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David SeynnaeveFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. david.seynnaeve@kuleuven.be.ORCID 0000-0002-2598-3934
Mara Del VecchioFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. mara.delvecchio@kuleuven.be.
Gernot FruhmannFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. gernot.fruhmann@kuleuven.be.
Joke VerelstFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. joke.verelst@kuleuven.be.
Melody CoolsFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. melody.cools@kuleuven.be.
Jimmy BeckersFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. jimmy.beckers@student.kuleuven.be.
Daniel P MulvihillSchool of Biosciences, University of Kent, Canterbury CT2 7NJ, Kent, UK. D.P.Mulvihill@kent.ac.uk.ORCID 0000-0003-2502-5274
Joris WinderickxFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. joris.winderickx@kuleuven.be.ORCID 0000-0003-3133-7733
Vanessa FranssensFunctional Biology, KU Leuven, Kasteelpark Arenberg 31, 3000 Leuven, Belgium. vanessa.franssens@kuleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review article, yeast model-based research advances regarding the role of Amyloid-β (Aβ), Tau and frameshift Ubiquitin UBB

Indexed as

Models, BiologicalAlzheimer DiseaseAmyloid beta-PeptidesAnimalsHumansKluyveromycesSaccharomyces cerevisiaeSchizosaccharomycestau ProteinsUbiquitinAmyloid beta-Peptidestau ProteinsUbiquitinaggregationAlzheimer’s diseaseamyloid βoligomerizationprionTauubiquitinyeast

Identifiers

PMID29970827
PMCPMC6073265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.