Evidence map›Paper›PMID 29970816›Full record

ArticleMedicines (Basel, Switzerland)2018

Optimisation of the Microwave-Assisted Ethanol Extraction of Saponins from Gac (

Anh V Le, Sophie E Parks, Minh H Nguyen, Paul D Roach

Abstract read
In one paragraph

Article in Medicines (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anh V LeSchool of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW 2258, Australia. vananh.le@uon.edu.au.ORCID 0000-0002-4209-7483
Sophie E ParksSchool of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW 2258, Australia. sophie.parks@dpi.nsw.gov.au.
Minh H NguyenSchool of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW 2258, Australia. Minh.Nguyen@newcastle.edu.au.
Paul D RoachSchool of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW 2258, Australia. Paul.Roach@newcastle.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGac (

resultsA four-fold higher total saponin content (TSC) was obtained in extracts from full-fat Gac seed kernel powder than from defatted powder (100 vs. 26 mg aescin equivalents (AE) per gram of Gac seeds). The optimal parameters for the extraction of saponins were a ratio of 30 mL of 100% absolute ethanol per g of full-fat Gac seed kernel powder with the microwave set at 360 W for three irradiation cycles of 10 s power ON and 15 s power OFF per cycle.

conclusionsGac seed saponins could be efficiently extracted using MAE. Full-fat powder of the seed kernels is recommended to be used for a better yield of saponins. The optimised MAE conditions are recommended for the extraction of enriched saponins from Gac seeds for potential application in the nutraceutical and pharmaceutical industries.

Indexed as

Gac seedsmicrowave-assisted extractionMomordica cochinchinensisoptimizationsaponins

Identifiers

PMID29970816
PMCPMC6165236

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.