ArticleLung India : official organ of Indian Chest Society
Factors influencing severity of community-acquired pneumonia.
Article in Lung India : official organ of Indian Chest Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Predictors of mortality in severe pneumonia patients: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Prevalence of atypical pathogens in patients with severe pneumonia: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Factors associated with severe pneumonia in adults hospitalised with community-acquired pneumonia in Mongolia.BMC public health · 2026Article
- Bacterial profile, antimicrobial susceptibility patterns, and associated factors among lower respiratory tract infection patients attending at Debre Markos comprehensive specialized hospital, Northwest, Ethiopia.BMC infectious diseases · 2025Article
- Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning.Frontiers in pharmacology · 2025Article
- Incidence and Risk Profiles for Suicide Mortality in Patients With Schizophrenia Receiving Homecare Case Management in Taiwan.Schizophrenia bulletin · 2024Article
- The relationship between neighborhood economic deprivation and community-acquired pneumonia related admissions in Maryland.Frontiers in public health · 2024Article
- Effect of Undernutrition and Obesity on Clinical Outcomes in Adults with Community-Acquired Pneumonia.Nutrients · 2022Review
- Prevalence, Antimicrobial Resistance, and Associated Factors ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Article
- Systematic review and meta-analysis of comorbidities and associated risk factors in Indian patients of community-acquired pneumonia.SAGE open medicine · 2022Review
- A literature review of severity scores for adults with influenza or community-acquired pneumonia - implications for influenza vaccines and therapeutics.Human vaccines & immunotherapeutics · 2021Review
- Multiresistant Bacterial Pathogens Causing Bacterial Pneumonia and Analyses of Potential Risk Factors from Northeast Ethiopia.International journal of microbiology · 2021Article
- Factors influencing severe community-acquired pneumonia few points to ponder.Lung India : official organ of Indian Chest SocietyArticle
- Author's reply.Lung India : official organ of Indian Chest SocietyArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionCommunity-acquired pneumonia (CAP) is a common cause of morbidity and mortality in India. There is a need to understand the risk factors associated with severity of CAP in our population. This study was part of the international global initiative for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia study to evaluate MRSA.
methodsA total of 100 consecutive cases of pneumonia admitted to the Department of Pulmonary Medicine in a tertiary care hospital were recruited in the study during March-July 2015. The severity of pneumonia was assessed based on the CURB-65 score. Individuals with pneumonia and CURB-65 score >2 were compared with subjects with CURB-65 score ≤2. Individuals were also evaluated for the causative organism and its resistance pattern with specific reference to the presence of MRSA.
resultsMean age of patients was 54.03 years, 66% were men. Patients were managed either in the intensive care unit (42%) or wards/high dependency unit (58%), 22% needed noninvasive ventilation and 18% needed mechanical ventilation within 24 h of admission. On multivariate analysis, prior respiratory infection (within last 1 year), obesity (body mass index >30), and alcoholism, old age (>60 years) were independently associated risk factors for severe pneumonia. There were no cases of MRSA. In 34% of cases, organisms could be identified. Most common organisms were Klebsiella (8%), influenza (8%), and Pseudomonas (5%).
conclusionPrior respiratory infection, obesity, alcoholism, and old age (>60 years) were observed to be important risk factors for severe CAP. Prospective studies should evaluate effect of weight reduction and cessation of alcohol consumption on recurrences of pneumonia in this population and on the severity of pneumonia.
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