Evidence map›Paper›PMID 29970489›Full record

ArticleGenetics2018

Condensin Depletion Causes Genome Decompaction Without Altering the Level of Global Gene Expression in

Matthew Robert Paul, Tovah Elise Markowitz, Andreas Hochwagen, Sevinç Ercan

Abstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. SMC complexes: Lifting the lid on loop extrusion.Current opinion in cell biology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. International journal of molecular sciences · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew Robert PaulDepartment of Biology, New York University, New York 10003.ORCID 0000-0002-3020-7729
Tovah Elise MarkowitzDepartment of Biology, New York University, New York 10003.
Andreas HochwagenDepartment of Biology, New York University, New York 10003 andi@nyu.edu se71@nyu.edu.ORCID 0000-0002-6184-443X
Sevinç ErcanDepartment of Biology, New York University, New York 10003 andi@nyu.edu se71@nyu.edu.ORCID 0000-0001-7297-1648

Funding

Mechanisms of Chromosome Scale Signal PropagationR01GM111715 · NIGMS · NEW YORK UNIVERSITY · PI HOCHWAGEN, ANDREAS · 2015 to 2022
$2.6M
Mechanisms of X chromosome dosage compensation in C. elegansR01GM107293 · NIGMS · NEW YORK UNIVERSITY · PI ERCAN, SEVINC · 2014 to 2018
$1.5M
Chromosomal control of meiotic double-strand break formationR01GM123035 · NIGMS · NEW YORK UNIVERSITY · PI HOCHWAGEN, ANDREAS · 2018 to 2021
$1.2M
NIGMS NIH HHS R01 GM107293NIGMS NIH HHS R01 GM111715NIGMS NIH HHS R01 GM123035
6 · The paper itself

Abstract

Condensins are broadly conserved chromosome organizers that function in chromatin compaction and transcriptional regulation, but to what extent these two functions are linked has remained unclear. Here, we analyzed the effect of condensin inactivation on genome compaction and global gene expression in the yeast

Indexed as

Adenosine TriphosphatasesCentromereChromatinDNA-Binding ProteinsDNA, RibosomalGene Expression Regulation, FungalGenomeMitosisMultiprotein ComplexesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscriptomeAdenosine TriphosphatasesChromatincondensin complexesDNA-Binding ProteinsDNA, RibosomalMultiprotein ComplexesSaccharomyces cerevisiae Proteinsbudding yeastchromosome interactionscondensingene expressiongenome organizationTADs

Identifiers

PMID29970489
PMCPMC6116964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.