Evidence map›Paper›PMID 29970473›Full record

ArticleThe Journal of experimental medicine2018

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation.

Isabelle C Arnold, Mariela Artola-Borán, Paulino Tallón de Lara, Andreas Kyburz, Christian Taube, Karen Ottemann, Maries van den Broek, Shida Yousefi, Hans-Uwe Simon, Anne Müller

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 133 citations in OpenAlex.

  1. Review
  2. Article
  3. Tissue adaptation of eosinophils.Journal of leukocyte biology · 2026
    Review
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Pleiotropic Mucosal Innate Immune Memory in the Gastrointestinal Tract.International journal of molecular sciences · 2025
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Isabelle C ArnoldInstitute of Molecular Cancer Research, University of Zürich, Zurich, Switzerland arnold@imcr.uzh.ch.ORCID 0000-0001-8679-9666
Mariela Artola-BoránInstitute of Molecular Cancer Research, University of Zürich, Zurich, Switzerland.
Paulino Tallón de LaraInstitute of Experimental Immunology, University of Zürich, Zurich, Switzerland.ORCID 0000-0001-7368-4798
Andreas KyburzInstitute of Molecular Cancer Research, University of Zürich, Zurich, Switzerland.
Christian TaubeDepartment of Pulmonary Medicine, University Hospital Essen-Ruhrlandklinik, Essen, Germany.
Karen OttemannDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, CA.ORCID 0000-0001-6265-7401
Maries van den BroekInstitute of Experimental Immunology, University of Zürich, Zurich, Switzerland.ORCID 0000-0002-9489-3692
Shida YousefiInstitute of Pharmacology, University of Bern, Bern, Switzerland.ORCID 0000-0002-9855-4305
Hans-Uwe SimonInstitute of Pharmacology, University of Bern, Bern, Switzerland.ORCID 0000-0002-9404-7736
Anne MüllerInstitute of Molecular Cancer Research, University of Zürich, Zurich, Switzerland.
University of Zurich · CHUniversity of Bern · CHRuhrlandklinik · DEUniversity of California, Santa Cruz · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophils are predominantly known for their contribution to allergy. Here, we have examined the function and regulation of gastrointestinal eosinophils in the steady-state and during infection with

Indexed as

Acute DiseaseAnimalsAntibodies, BacterialBacterial InfectionsCell DegranulationCell ProliferationCitrobacter rodentiumColitisCytokinesDisease Models, AnimalEosinophilsExtracellular TrapsGastrointestinal TractHelicobacter pyloriHomeostasisImmunity, InnateAntibodies, BacterialCytokinesInterferon-gamma

Identifiers

PMID29970473
PMCPMC6080907
OpenAlexW2810886351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.