Evidence map›Paper›PMID 29970452›Full record

ArticleGenome research2018

Massive variation of short tandem repeats with functional consequences across strains of

Maximilian O Press, Rajiv C McCoy, Ashley N Hall, Joshua M Akey, Christine Queitsch

Abstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  18. Natural variation inGenome research · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maximilian O PressDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0001-9233-2157
Rajiv C McCoyDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Ashley N HallDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Joshua M AkeyDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Christine QueitschDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.

Funding

TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0M
Does organismal robustness explain the missing heritability in complex diseases?DP2OD008371 · OD · UNIVERSITY OF WASHINGTON · PI QUEITSCH, CHRISTINE · 2011 to 2011
$2.3M
Ribosomal DNA copy number variation as a source of missing heritability in complex traitsR01GM122088 · NIGMS · UNIVERSITY OF WASHINGTON · PI QUEITSCH, CHRISTINE · 2017 to 2019
$1.4M
NIGMS NIH HHS R01 GM122088NIGMS NIH HHS T32 GM007270NIH HHS DP2 OD008371
6 · The paper itself

Abstract

Short tandem repeat (STR) mutations may comprise more than half of the mutations in eukaryotic coding DNA, yet STR variation is rarely examined as a contributor to complex traits. We assessed this contribution across a collection of 96 strains of

Indexed as

AllelesArabidopsisDNA Copy Number VariationsGenotypeMicrosatellite RepeatsMutationPolymorphism, Single Nucleotide

Identifiers

PMID29970452
PMCPMC6071631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.