Evidence map›Paper›PMID 29970132›Full record

ArticleBMC research notes2018

Profile of the 2016 dengue outbreak in Nepal.

Ramawatar Prasad Khetan, David A Stein, Santosh Kumar Chaudhary, Ramanuj Rauniyar, Bishnu Prasad Upadhyay, Umesh Prasad Gupta, Birendra Prasad Gupta

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In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. The alarming outbreaks of dengue in Nepal.Tropical medicine and health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ramawatar Prasad KhetanMB Kedia Dental College Private Limited, Birgunj, Tribhuvan University, Kathmandu, Nepal.
David A SteinDepartment of Biomedical Sciences, Oregon State University, Corvallis, OR, USA.
Santosh Kumar ChaudharyMB Kedia Dental College Private Limited, Birgunj, Tribhuvan University, Kathmandu, Nepal.
Ramanuj RauniyarVirology Unit, Central Department of Biotechnology, Tribhuvan University, Kathmandu, Nepal.
Bishnu Prasad UpadhyayNational Public Health Laboratory, Ministry of Health, Government of Nepal, Kathmandu, Nepal.
Umesh Prasad GuptaCentral Diagnostic Laboratory and Research Centre Pvt. Ltd, Kathmandu, Nepal.
Birendra Prasad GuptaVirology Unit, Central Department of Biotechnology, Tribhuvan University, Kathmandu, Nepal. birendraphd@gmail.com.ORCID http://orcid.org/0000-0001-6477-6260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to obtain clinical, virological and demographic data detailing the 2016 dengue outbreak in Nepal.

resultsDengue disease was first reported in Nepal in 2004 and several major outbreaks have occurred since then, with a significant impact on public health. An outbreak of dengue fever occurred in Nepal during June to November 2016, with a peak number of cases reported in September. 1473 patients with laboratory confirmed DENV infections visited or were admitted to hospitals during this period. The most common clinical symptoms included fever, headache, joint pain and thrombocytopenia. Serotyping of 75 serum samples from patients having fever for less than 4 days was carried out with a dengue virus (DENV) serotype-specific RT-PCR strategy. Our results indicate that the dengue outbreak in Nepal during 2016 was caused predominantly, if not exclusively, by DENV-1, representing a shift in the prevailing serotype from DENV-2, the dominant serotype characterizing the 2013 dengue epidemic in Nepal. Hopefully, this report will assist Nepalese public health agencies in developing improved dengue-related programs including mosquito-vector control, DENV surveillance, and diagnosis and treatment of dengue fever patients, in order to reduce the impact of future dengue epidemics.

Indexed as

Disease OutbreaksAdultAnimalsDengueFemaleHumansMaleMiddle AgedNepalYoung AdultDengue feverDengue virus serotype 1NepalOutbreak

Identifiers

PMID29970132
PMCPMC6029055

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.