Evidence map›Paper›PMID 29970130›Full record

Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2018

Acute pain in the prehospital setting: a register-based study of 41.241 patients.

Kristian D Friesgaard, Ingunn S Riddervold, Hans Kirkegaard, Erika F Christensen, Lone Nikolajsen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. The effectiveness and safety of paediatric prehospital pain management: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021
    Pooled it
  2. Trial
  3. Observational
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  6. Review
  7. Observational
  8. Article
  9. Article
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  11. Article
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  13. Pain assessment and management of adult patients in the Swedish EMS: a nationwide registry study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Observational
  14. Observational
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kristian D FriesgaardResearch Department, Prehospital Emergency Medical Service, Central Denmark Region, Aarhus, Denmark. k.friesgaard@me.com.
Ingunn S RiddervoldResearch Department, Prehospital Emergency Medical Service, Central Denmark Region, Aarhus, Denmark.
Hans KirkegaardResearch Department, Prehospital Emergency Medical Service, Central Denmark Region, Aarhus, Denmark.
Erika F ChristensenDepartment of Clinical Medicine, Center for Prehospital and Emergency Research, Aalborg University, Aalborg, Denmark.
Lone NikolajsenDepartment of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark.
Central Denmark Region · DKAarhus University Hospital · DKNorth Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pain is a frequent symptom, but little is known about the frequency and causes of acute pain in the prehospital population. The objectives of this study were to investigate the frequency of moderate to severe pain among prehospital patients and the underlying causes according to primary hospital diagnose codes.

methodsThis was a register-based study on 41.241 patients transported by ambulance. Information on moderate to severe pain [Numeric Rating Scale (NRS, 0-10) > 3 or moderate pain or higher on 4-point likert scale] was extracted from a national electronic prehospital patient record. Patient information was merged with primary hospital diagnose codes based on the 10th version of the International Classification of Diseases (ICD-10) to investigate underlying causes of pain.

results11.430 patients (27.7%) reported moderate to severe pain during ambulance transport. As a measure of opioid demanding acute pain, 3.275 of 41.241 patients (7.9%) were treated with intravenous fentanyl. Underlying causes of pain were heterogenic according to ICD-10 chapters with injuries being the largest group of patients with moderate to severe pain (XIX: 42.8% of 8.041 patients), followed by non-specific diagnoses (XVIII: 28.5% of 7.101 patients and XXI: 31.6% of 5.148 patients), diseases of the circulatory system (IX: 22.1% of 4.812 patients) and other (20.3% of 16.139 miscellaneous patients). DISCUSSION: Due to the high frequency of moderate to severe pain affecting a wide range of patients, more attention on acute pain is necessary. Whether ambulance personnel have sufficient options for treating various pain conditions might be a subject of future evaluation. Non-specific diagnoses accounted for surprisingly many patients with moderate to severe pain, of which many were treated with intravenous fentanyl. This may be substance of further investigation.

conclusionsModerate to severe pain is a highly frequent and probably underestimated symptom among patients transported by ambulance. Underlying causes of pain are heterogenic as described by primary hospital diagnose codes. More focus on the treatment of acute pain is needed.

Indexed as

AmbulancesPain ManagementPain MeasurementAcute PainAdultAnalgesics, OpioidDenmarkFemaleFentanylHospitalizationHumansMaleMiddle AgedAnalgesics, OpioidFentanylAcute painCauses of acute painPrehospital

Identifiers

PMID29970130
PMCPMC6029421
OpenAlexW2810252854

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.