Evidence map›Paper›PMID 29970128›Full record

SynthesisParasites & vectors2018

Plasmodium and intestinal parasite perturbations of the infected host's inflammatory responses: a systematic review.

Aminata Colle Lo, Babacar Faye, Ben Adu Gyan, Linda Eva Amoah

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Bugs as drugs: parasite biomolecules as novel therapeutics against breast cancer.American journal of physiology. Cell physiology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. UnderstandingFrontiers in immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Aminata Colle LoNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Babacar FayeUniversity Cheikh Anta DIOP, Dakar, Senegal.
Ben Adu GyanNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Linda Eva AmoahNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana. lamoah@noguchi.ug.edu.gh.
Noguchi Memorial Institute for Medical Research · GHCheikh Anta Diop University · SNUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Co-infection of malaria and intestinal parasites is widespread in sub-Saharan Africa and causes severe disease especially among the poorest populations. It has been shown that an intestinal parasite (helminth), mixed intestinal helminth or Plasmodium parasite infection in a human induces a wide range of cytokine responses, including anti-inflammatory, pro-inflammatory as well as regulatory cytokines. Although immunological interactions have been suggested to occur during a concurrent infection of helminths and Plasmodium parasites, different conclusions have been drawn on the influence this co-infection has on cytokine production. This review briefly discusses patterns of selected cytokine (IL-6, IL-8, IL-10, TNF-α and INF-γ) responses associated with infections caused by Plasmodium, intestinal parasites as well as a Plasmodium-helminth co-infection.

Indexed as

AnimalsCoinfectionCytokinesFemaleHelminthiasisHost-Parasite InteractionsHumansInflammationInterferon-gammaInterleukin-10Intestinal Diseases, ParasiticIntestinesMalariaMicePlasmodiumCytokinesIL10 protein, humanInterferon-gammaInterleukin-10

Identifiers

PMID29970128
PMCPMC6031113
OpenAlexW2811098875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.