ReviewWorld journal of surgical oncology2018
Schwannoma of the colon and rectum: a systematic literature review.
Review in World journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 74 citations in OpenAlex.
- Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas.BioMed research international · 2020Trial
- Rectal schwannoma mimicking malignant rectal cancer: a case report.International journal of surgery case reports · 2026Article
- Management of Gastrointestinal Schwannomas: A State-of-the-Art Review.Journal of gastrointestinal cancer · 2026Review
- Incidental ileal schwannoma mimicking acute appendicitis: an intraoperative diagnostic challenge.Journal of surgical case reports · 2026Article
- Case Report: Benign colonic schwannoma with restricted diffusion mimicking malignancy.Frontiers in oncology · 2026Article
- Successful Sphincter-Preserving Resection of a Giant Rectal Schwannoma Using Transanal Total Mesorectal Excision: A Case Report.Surgical case reports · 2026Article
- Malignant peripheral nerve sheath tumor of the ileocecal region: a case report.Frontiers in oncology · 2026Article
- Dual Tumor Pathogenesis in the Gastrointestinal Tract: Synchronous Rectal Schwannoma and Gallbladder Papillary Adenocarcinoma-A Case Report.Reports (MDPI) · 2025Article
- Schwannoma of the colon presenting as a submucosal lesion: diagnostic challenge and surgical management.Journal of surgical case reports · 2025Article
- Gastrointestinal schwannomas: A case series of 9 patients and literature review.Turkish journal of surgery · 2025Article
- Cecal schwannoma: A case report and literature review.The Journal of international medical research · 2025Review
- Ancient schwannoma-a rare cause of mesenteric root expansion.Journal of surgical case reports · 2025Article
- Mucosal Schwann Cell Hamartoma of the Appendix: Expanding the Differential for Gastrointestinal Bleeding.ACG case reports journal · 2025Article
- Unveiling the Rare: A Case Report of Rectal Schwannoma in a Neurofibromatosis Type 1 Patient.Cureus · 2025Article
- Endoscopic full-thickness resection of rectal schwannoma: A case report.World journal of gastrointestinal endoscopy · 2025Article
- Article
- Comprehensive analysis of diagnosis and treatment in 99 cases of abdominal Schwannoma.Cancer medicine · 2024Article
- Schwannoma in the Rectum: A Case Report.Cureus · 2024Article
- Rare retroperitoneal giant sacral schwannoma: A case report.Oncology letters · 2024Article
- Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSchwannomas of the colon and rectum are rare among gastrointestinal schwannomas. They are usually discovered incidentally as a submucosal mass on routine colonoscopy and diagnosed on pathologic examination of the operative specimen. Little information exists on the diagnosis and management of this rare entity. The aim of this study is to report a case of cecal schwannoma and the results of a systematic review of colorectal schwannoma in the literature. MAIN BODY: PubMed, Scopus, and Cochrane database searches were performed for case reports and case series of colonic and rectal schwannoma. Ninety-five patients with colonic or rectal schwannoma from 70 articles were included. Median age was 61.5 years (59% female). Presentation was asymptomatic (28%), rectorrhagia (23.2%), or abdominal pain (15.8%). Schwannoma occurred in the left and sigmoid colon in 36.8%, in the cecum and right colon in 30.5%, and in the rectum in 21.1%. Median tumor size was 3 cm and 56.2% of patients who underwent preoperative colonoscopy had a typical smooth submucosal mass. At pathology, 97.9, 13.7, and 5.3% of schwannomas stained positive for S100, vimentin, and GFAP, respectively. The median mitotic index was 1/50.
conclusionsColorectal schwannoma is a very rare subtype of gastrointestinal schwannoma which occurs in the elderly, almost equally in men and women. Schwannoma should be included in the differential diagnosis of a submucosal lesion along with gastrointestinal stromal tumor, neuro-endocrine tumors, and leiomyoma-leiomyosarcoma. Definitive diagnosis is based on immunohistochemistry of the operative specimen. Rarely malignant, surgery is the mainstay of treatment.
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