Evidence map›Paper›PMID 29970020›Full record

ArticleBMC infectious diseases2018

Group B streptococcal colonization in mothers and infants in western China: prevalences and risk factors.

Jichang Chen, Jinjian Fu, Wei Du, Xin Liu, Chokechai Rongkavilit, Xuemei Huang, Yubi Wu, Yuanliu Wang, Eric McGrath

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Vertical Transmission of Group BInternational journal of microbiology · 2024
    Article
  5. Colonisation of Group BBMJ open · 2023
    Article
  6. Article
  7. Article
  8. Diagnostic Performance of Various Methodologies for Group B SFrontiers in cellular and infection microbiology · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. [Group B streptococcus colonization in pregnant women and group B streptococcus infection in their preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Article
  13. Article
  14. Prevalence, risk factors, and serotypes of group BTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jichang ChenDepartment of Neonatology, Liuzhou Maternity and Child Health Care Hospital, Liuzhou, 545001, China.
Jinjian FuDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, 545001, China.
Wei DuChildren's Hospital of Michigan, Detroit, MI, USA.
Xin LiuDepartment of Pediatrics, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, 545001, China.
Chokechai RongkavilitDepartment of Infectious Diseases, Valley Children's Hospital, Madera, CA, USA.
Xuemei HuangDepartment of Neonatology, Liuzhou Maternity and Child Health Care Hospital, Liuzhou, 545001, China.
Yubi WuDepartment of Obstetrics and Gynecology, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, 545001, China.
Yuanliu WangDepartment of Obstetrics and Gynecology, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, 545001, China.
Eric McGrathChildren's Hospital of Michigan, Detroit, MI, USA. emcgrath@med.wayne.edu.ORCID 0000-0003-1542-6488

Funding

Guanxi Medical and Health Self-Funding Project Z2015188, Z20170543
6 · The paper itself

Abstract

backgroundThe epidemiology of maternal and infant Group B streptococcus (GBS) colonization is poorly understood in China. The aim of this study is to explore the prevalence and risk factors associated with maternal and infant GBS colonization in Western China.

methodsFrom January 2017 to June 2017, a prospective study was conducted to estimate the maternal and infant GBS colonization rate by maternal rectovaginal and infant nasopharynx, ear canal and umbilical swab culture. Patient demographics, clinical characteristics and outcomes were collected. Chi-square and logistic regression analyses were used to examine the risk factors associated with GBS colonization of mothers and infants.

resultsThe GBS colonization rate in mothers and infants was 6.1 and 0.7%, respectively. The vertical transmission rate was 7.6%. The early onset GBS infection rate was 0.58 per 1000 live births and mortality was 0.29 per 1000 live births. Age younger than 40 years (p = 0.040) and minority ethnic status (p = 0.049) were associated with higher GBS colonization rate in pregnant women. Positive GBS status in the mother prior to delivery (p < 0.001) as well as longer duration of membrane rupture (≥12 h) (p < 0.001) and longer labor (≥4 h) (p < 0.001) were all significant risk factors for GBS colonization in infants. Compared to infants without GBS colonization, infants colonized with GBS were more likely to have had a temperature of ≥38 °C (p < 0.001), developed early onset infection (EOD) (p < 0.001), and been prescribed antibiotics (p < 0.001). Furthermore, infants with GBS were more likely to have been admitted to neonatal intensive unit (NICU) (p < 0.001) with a longer hospital length of stay (LOS) (p < 0.001).

conclusionsMaternal GBS colonization, longer duration of membrane rupture and labor were all major risk factors associated with GBS colonization in Chinese infants. Infant GBS colonization was associated with increased risk of EOD and NICU admission as well as longer LOS.

Indexed as

Infectious Disease Transmission, VerticalStreptococcus agalactiaeAdolescentAdultAnti-Bacterial AgentsChinaFemaleHumansInfant, NewbornMaleMothersNasopharynxPregnancyPregnancy Complications, InfectiousPrevalenceProspective StudiesAnti-Bacterial AgentsEarly onset disease (EOD)GBS colonizationGroup B streptococcusMother-infant pairs

Identifiers

PMID29970020
PMCPMC6029028

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.